New protein implant could improve spinal fusion outcomes

NCT ID NCT07217964

ENROLLING_BY_INVITATION Disease control Sponsor: Hospital for Special Surgery, New York Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at a natural protein called Natural Matrix Protein (NMP) used as a bone graft substitute during lumbar spinal fusion surgery. Researchers will review the medical records of about 100 adults who had this surgery to see how well their bones fused and if there were any complications. The goal is to find out if NMP is a safe and effective option for helping bones heal together in the spine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Natural Matrix Protein (NMP) bioimplant
What this could lead to: If successful, NMP could offer a safer or more effective alternative to traditional bone grafts for spinal fusion surgery.
What could go wrong: This is a small, non-randomized study with no control group, so results may not be definitive. The intervention is surgical, carrying standard risks like infection or non-union.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lumbar disk degenerative disorder lumbar disk disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENERATIVE LUMBAR SPINAL CONDITIONS

Contacts and locations

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Locations

Hospital for Special Surgery

New York, New York, 10021, United States

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