Cure My Disease

Don't miss your cure!

 Log in / Sign up

Dye test helps spine surgeons see if They've cleaned enough

NCT ID NCT07363759

Knowledge-focused Sponsor: Rush University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injecting a contrast dye into the disc space during TLIF spine surgery helps surgeons assess how well they have removed the disc. 56 patients having spinal fusion for degenerative spine disease were randomly assigned to either have the dye used as a check or as a guide to do more cleaning. The goal was to see if the dye improves the quality of disc space preparation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ISOVUE-300 contrast dye
What this could lead to
If successful, this technique could give surgeons real-time feedback to improve disc preparation during spinal fusion surgery.
What could go wrong
This is a small, completed trial with 56 patients. The dye is only used during surgery to guide the procedure, not to treat the underlying spine condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Apr 2019

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 100 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing open circumferential transforaminal lumbar interbody fusion or midline cortical TLIF for degenerative spondylolisthesis Exclusion Criteria: * All not in the group above

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Degenerative spine are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder spondylolisthesis spondylosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Degenerative spine Lumbar degenerative disc disease Lumbar degenerative disease

Contacts and locations

Locations

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.