Rush University Medical Center

This study looks at a procedure called cardioneuroablation for people under 60 who faint often due to vasovagal syncope. The procedure uses radiofrequency energy to target nerve clusters in the heart, aiming to prevent fainting without needing a permanent pacemaker. Researchers w…

This study tests a 12-month church-based program to help African Americans with uncontrolled high blood pressure lower their numbers. About 312 adults from churches with mostly African American members will join. The program focuses on healthy eating, medication adherence, and li…

This study tests a pharmacist-led program to help adults with uncontrolled high blood pressure in underserved Chicago communities. Over 3 months, a mobile team provides blood pressure checks, medication management, and health education. The goal is to lower blood pressure and imp…

This study tests a self-management program for people with COPD to see which parts work best to reduce hospital stays and improve daily life. Researchers will enroll 448 adults aged 40+ who have had a COPD-related hospitalization in the past year. Participants will use a smartpho…

This study tests whether treating PTSD symptoms soon after acute pain starts can stop the pain from becoming chronic. Researchers will use either a nerve block (stellate ganglion block) or talk therapy (Cognitive Processing Therapy) in 345 adults with PTSD and acute pain. The goa…

This study tests whether a nerve block called an erector spinae plane block (ESPB) can quickly reduce low back pain in adults visiting the emergency department. About 62 participants will receive either the ESPB or a placebo injection. Researchers will track pain levels for up to…

This study tests whether morning bright light therapy can improve gut health and quality of life in people with Crohn's disease or ulcerative colitis. Researchers will measure changes in intestinal barrier function, inflammation, and gut bacteria. The study enrolls 30 adults with…

This study looks at whether turning a nerve stimulator on and off (30 seconds on, 90 seconds off) works as well as leaving it on all the time for people with chronic pain from conditions like CRPS, radiculopathy, or peripheral neuropathy. About 30 adults who have had a spinal ner…

This study tests two different vibrating devices that help people with trouble clearing mucus from their lungs. Researchers want to see which device works better. The study will include 64 adults who have trouble clearing airway secretions.

This study tests a program called NurseNET, where trained nurses provide a short-term therapy for PTSD in primary care. About 100 adults with PTSD symptoms will receive 4 to 6 sessions of Narrative Exposure Therapy. The goal is to see if this approach reduces PTSD symptoms and is…

This study tests whether the KRONOS knee brace works better than the standard Breg T-Scope brace for people recovering from ACL reconstruction surgery. About 40 adults who are having their first ACL surgery will wear one of the two braces after their operation. The goal is to see…

This study tests a new drug called (2R,6R)-HNK to see if it can reduce nerve pain in the arms or legs. About 25 adults with chronic nerve pain will receive the drug, ketamine, or a placebo in random order. Researchers will measure pain levels, daily function, and sleep quality ov…

This study tests a new guidance tool called Ablation Index to help doctors perform heart ablation more precisely in people with ventricular tachycardia (a fast, dangerous heart rhythm) and ischemic cardiomyopathy (weakened heart muscle from past heart attacks). The goal is to see…

This study looks at whether ICU doctors, nurses, and other clinicians make better predictions about a patient's chance of surviving one year when they are given a special risk score called ProVent-14. The score uses simple medical information measured on day 14 of being on a brea…

This study looks at whether pulse oximeters—the clips placed on your finger to measure oxygen—are less accurate for people with darker skin. Researchers will compare the device's readings to oxygen levels measured directly from blood in 194 adults already having a blood test. The…

This study looks at why people with lower incomes often have a harder time losing weight in behavioral programs. Researchers will track daily experiences and decision-making patterns in 230 adults with obesity. The goal is to uncover the hidden reasons behind these disparities, n…

This study tests whether showing people a real-time ultrasound of their heart in the emergency room, along with standard education, helps them understand their heart failure risk and motivates them to improve diet, exercise, and see a doctor. About 100 adults aged 45+ with high b…

This study looks at whether the time of day a breathing test is done affects how quickly ICU patients can stop using a ventilator. About 348 adults who have been on a ventilator for more than two days will be split into two groups: one gets the test early in the morning, the othe…

This study looks at what to do when the first PTSD treatment doesn't work. Researchers will test different proven therapies on 400 adults who still have PTSD after initial treatment. The goal is to find out which second treatment works best and create a tool to identify early who…

This study tests whether a new nerve monitoring device (NeuroVision) can better prevent nerve damage during spine surgery compared to standard hospital monitoring. About 148 adults having lateral spine surgery will be randomly assigned to one of the two monitoring methods. The ma…