Rush University Medical Center

This study tests whether using a device to precisely control breathing during CPR improves outcomes for adults who have a cardiac arrest in the hospital. About 852 participants will be randomly assigned to either standard manual breathing or breathing guided by real-time feedback…

This study looks at people with deep vein thrombosis (a blood clot in the leg) that hasn't improved after a week of blood thinners. It tests whether adding catheter-based treatments (medication or clot removal) can help. About 100 adults aged 18-75 will be randomly assigned to ei…

This study looks at two treatments for people with a sudden ACL tear and knee swelling: draining excess joint fluid or injecting a blood-derived substance called PRP. The goal is to see if these steps lower harmful inflammation before surgery, which might help prevent long-term k…

This study tests whether a vaginal injection of ketorolac (an anti-inflammatory) plus lidocaine (a numbing drug) can reduce pain when placing osmotic dilators for second-trimester abortion. About 76 adults will receive either the combined injection or standard care. The goal is t…

This study tests whether taking tranexamic acid pills for up to 7 days after knee replacement surgery improves pain, function, and range of motion compared to a placebo. About 351 adults having knee replacement will be randomly assigned to receive the drug or a dummy pill. The go…

This study tests a tailored mindfulness program (MAP) against a health education program in 30 older adults with mild cognitive impairment and high stress. The goal is to see if mindfulness can reduce stress and improve memory, mood, and well-being. Participants will be followed …

This study involves 60 speech-language pathologists who will look at images of food residue in the throat and decide whether to restrict a patient's diet. Half will watch an educational video first to see if it changes their decisions. The goal is to understand how much residue i…