Rush University Medical Center

This study tests two procedures done before ACL surgery: draining excess knee joint fluid (arthrocentesis) or injecting platelet-rich plasma (PRP) from the patient's own blood. The goal is to see if either reduces inflammatory chemicals linked to cartilage damage. About 99 adults…

This study gives 400 adults with diabetes or high blood pressure free home-delivered produce boxes and vouchers for 6 months, plus nutrition education and self-management classes. The goal is to see if this helps them eat more fruits and vegetables, feel less food insecure, and i…

This study tests whether using special devices to precisely control breathing during CPR can help more people survive a cardiac arrest. About 852 adults who have a cardiac arrest in the hospital will be randomly assigned to either standard manual breathing help or breathing tailo…

This study tests whether using a catheter to deliver clot-busting drugs or a device to physically remove the clot can help people with acute deep vein thrombosis (DVT) who do not improve after one week of blood thinners. About 100 adults aged 18 to 75 with acute DVT in the leg wi…

This study looks at ways to help Black women get PrEP, a daily pill that prevents HIV. Researchers will try special strategies at family planning clinics to see if more women start and stay on PrEP. About 250 women with a recent STI will take part.

This study tests whether losartan, a common blood pressure medicine that also reduces scarring, can prevent abnormal scar tissue (arthrofibrosis) in the knee after ACL reconstruction. About 144 adults having ACL surgery will take losartan or a placebo. The main goal is to see if …

This study tests whether a paracervical block (an injection near the cervix) containing ketorolac and lidocaine can reduce pain during placement of osmotic dilators, which are used to prepare the cervix for a second-trimester abortion. About 76 participants will be randomly assig…

This study tests whether taking the drug tranexamic acid for up to 7 days after total knee replacement can improve pain, function, and knee movement. About 351 adults having knee surgery will be randomly assigned to take the drug for 3 days, 7 days, or a placebo. Researchers will…

This pilot study will test whether a specially designed mindfulness program, called Mindful Awareness Practice (MAP), can reduce stress and improve memory, mood, and well-being in older adults (65+) with mild cognitive impairment and high stress. Thirty participants will be rando…

This study looks at whether a standard step-by-step plan can help adults on high-flow oxygen therapy stop it more quickly and safely. About 2,000 patients across 8 hospitals will be involved. The goal is to see if the plan leads to more patients successfully coming off oxygen wit…

This study looks at how speech-language pathologists decide whether to restrict a patient's diet based on food residue seen in the throat during a swallowing test (FEES). Sixty therapists will review images of residue and indicate if they would restrict eating. Half will also wat…