Rush University Medical Center
Clinical trials sponsored by Rush University Medical Center, explained in plain language.
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Special program aims to close racial gap in blood pressure control
Disease control CompletedThis study tested a 12-week program to help African American and Latinx patients better manage their high blood pressure. A team including a community health worker, nurse, pharmacist, and social worker provided support and education. Patients used a cellular-connected blood pres…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Do hip replacement patients really need strict movement rules?
Disease control CompletedThis study tested whether strict movement restrictions after hip replacement surgery are necessary to prevent dislocation. Over 1,100 patients with hip arthritis were randomly assigned to follow the usual precautions or not. Researchers measured dislocation rates, how quickly pat…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Neck injection could boost PTSD therapy success
Disease control CompletedThis study tested if adding a simple neck injection to a standard PTSD therapy could make the therapy work better. Researchers compared the standard therapy alone to the therapy combined with either a real or a fake (placebo) injection. The goal was to see if the combination coul…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Brain zaps tested to help veterans stuck in PTSD treatment
Disease control CompletedThis small pilot study explored whether a non-invasive brain stimulation technique could help veterans with PTSD who weren't improving during the first week of a standard two-week intensive therapy program. Researchers combined the therapy with a procedure called iTBS, which uses…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New dye helps surgeons see inside the spine during surgery
Diagnosis CompletedThis study tested a new technique using a special contrast dye to help surgeons see how well they were removing disc material during a common spinal fusion surgery called TLIF. Researchers compared outcomes between patients where surgeons used this visual feedback and those who u…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Diagnosis
Last updated Mar 17, 2026 12:55 UTC
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Free pumps and pickup aim to close breast milk gap for tiniest infants
Prevention CompletedThis study tested whether providing practical support helps mothers of very small premature babies continue providing their own breast milk. Researchers gave some mothers free hospital-grade breast pumps, arranged for pumped milk to be picked up from their homes, and compensated …
Phase: NA • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated Apr 01, 2026 14:41 UTC
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New program trains young dads before baby arrives
Prevention CompletedThis study tested a new way to help young expectant parents prepare for their baby by including fathers in prenatal care. The program offered online education on infant care, relationship skills, and job support to 216 young couples. Researchers wanted to see if this approach lea…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated Mar 31, 2026 12:11 UTC
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Brain and body workout may shield memory in At-Risk women
Prevention CompletedThis study tested whether a 24-week home-based program of physical activity and brain training could prevent or delay memory loss in older women with heart disease. Researchers enrolled 253 women aged 65 and older who were at high risk for memory decline. They compared different …
Phase: NA • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated Mar 30, 2026 14:32 UTC
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New plan puts birth control on the Baby's doctor visit checklist
Prevention CompletedThis study tested a new way to help mothers get birth control after having a baby. Researchers tried offering contraception during the baby's first few doctor visits instead of making the mother come back for a separate appointment weeks later. The goal was to make it easier for …
Phase: NA • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated Mar 30, 2026 14:29 UTC
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App aims to ease pain for dying patients at home
Symptom relief CompletedThis study tested a digital app designed to help hospice patients and their caregivers manage pain at home. The app provides education about pain medication, makes it easier to report pain to nurses, and helps people follow their pain management plan. Researchers wanted to see if…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Apr 01, 2026 23:41 UTC
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Home therapy vs. clinic visits: which works better after shoulder surgery?
Symptom relief CompletedThis study aimed to find out if patients recover better after a reverse shoulder replacement by doing exercises at home with a surgeon's guidance or by attending formal physical therapy sessions at a clinic. Researchers followed 100 patients with severe shoulder arthritis or rota…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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New hope for less painful knee replacements?
Symptom relief CompletedThis study tested if the medication duloxetine could help reduce pain and the need for opioid painkillers after total knee replacement surgery. It involved 241 adults having knee replacement for arthritis, including some with a condition that makes them extra sensitive to pain. P…
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Mar 12, 2026 13:52 UTC
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Teens test digital anxiety helper in doctor visits
Knowledge-focused CompletedThis study tested a digital system called TeACH to help teens understand and manage anxiety during primary care visits. Researchers worked with 365 teens from underserved communities to design and implement the tool in clinics. The goal was to see if teens would use digital menta…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Late nights sabotage morning light therapy for teen sleep, study finds
Knowledge-focused CompletedThis study aimed to understand why morning bright light therapy, which can help shift a teenager's sleep schedule earlier, sometimes doesn't work. Researchers tested 88 healthy teens aged 14-17 to see how staying up late under normal home lighting and getting less sleep affects t…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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AI steps in to help doctors communicate with anxious ICU families
Knowledge-focused CompletedThis small pilot study tested whether artificial intelligence could help solve a common problem in intensive care units: giving families clear, daily written updates without overburdening busy doctors and nurses. Researchers had ICU clinicians review and edit AI-generated summari…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Doctors use ultrasound to see inside lungs of critically ill patients
Knowledge-focused CompletedThis study aimed to understand why turning critically ill patients onto their stomachs (prone positioning) helps some people with severe lung failure, including from COVID-19. Researchers used lung ultrasounds to take pictures of patients' lungs before and after they were turned …
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Massive study tracks 6,000 people to unlock COVID's Long-Term secrets
Knowledge-focused CompletedThis study aimed to understand the long-term health effects of COVID-19 by tracking 6,000 adults who had symptoms and were tested for the virus. Participants completed online surveys every 3 months for 18 months to share information about their health. The research focused on ide…
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Scientists test breathing machines on healthy volunteers to find best settings
Knowledge-focused CompletedThis study tested how different airflow settings on two new high-flow nasal oxygen devices affect lung volume and comfort in healthy adults. Twenty-six healthy volunteers tried the devices at various settings while researchers measured their lung volume and asked about comfort. T…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Cancer Drug's hidden vitamin drain: can a simple pill keep treatment on track?
Knowledge-focused CompletedThis study looked at whether the cancer drug olaparib causes a folic acid (folate) deficiency in patients with advanced ovarian or breast cancer. Researchers wanted to see how often this happens and if giving patients a folic acid vitamin supplement could prevent the deficiency. …
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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Researchers ask: what would get you into a medical trial?
Knowledge-focused CompletedThis study aimed to find out what would make clinical trials more appealing to people from diverse backgrounds, who are often underrepresented in medical research. Researchers surveyed 800 adults across the U.S. about their preferences for things like how results are shared and t…
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:28 UTC