Could a common antidepressant ease knee surgery pain?
NCT ID NCT05086393
First seen Nov 14, 2025 · Last updated May 01, 2026 · Updated 16 times
Summary
This study looked at whether duloxetine, a medication usually used for depression, can help reduce pain and the need for strong painkillers after knee replacement surgery. 241 adults having knee replacement took part. The goal was to see if adding duloxetine to standard pain treatment improves recovery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Rush University medical Center
Chicago, Illinois, 60612, United States
Conditions
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