Cure My Disease

Don't miss your cure!

 Log in / Sign up

Common surgical dressing may trigger allergic reactions in some joint replacement patients

NCT ID NCT06011603

Knowledge-focused Sponsor: Rush University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study looks at whether people who have had a Prineo dressing before are more likely to develop an allergic skin reaction when it is used again after joint replacement surgery. Researchers will compare first-time users with those who have had the dressing in the past, tracking redness, itching, and other skin problems. The goal is to better understand how common these reactions are and whether prior exposure increases risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Prineo dressing (2-octyl cyanoacrylate and n-butyl-2-cyanoacrylate adhesive)
What this could lead to
If it works, this could help surgeons choose safer dressings and reduce wound complications after joint replacement.
What could go wrong
This is an observational study, not a treatment trial. It only measures allergy rates and cannot prove cause or improve outcomes directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

303 people

The number who actually took part.

Started

Aug 2023

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients older than 18 years that underwent primary total joint arthroplasty (total hip, total knee, partial knee) Exclusion Criteria: * Revision surgery * Prior history of allergic contact dermatitis

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Allergic reaction are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

allergic disease hypersensitivity reaction disease injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Allergic reaction Wound complication

Contacts and locations

Locations

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.