Common surgical dressing may trigger allergic reactions in some joint replacement patients

NCT ID NCT06011603

Completed Knowledge-focused Sponsor: Rush University Medical Center Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study looks at whether people who have had a Prineo dressing before are more likely to develop an allergic skin reaction when it is used again after joint replacement surgery. Researchers will compare first-time users with those who have had the dressing in the past, tracking redness, itching, and other skin problems. The goal is to better understand how common these reactions are and whether prior exposure increases risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Prineo dressing (2-octyl cyanoacrylate and n-butyl-2-cyanoacrylate adhesive)
What this could lead to: If it works, this could help surgeons choose safer dressings and reduce wound complications after joint replacement.
What could go wrong: This is an observational study, not a treatment trial. It only measures allergy rates and cannot prove cause or improve outcomes directly.

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Conditions

The condition(s) this trial relates to.

allergic disease hypersensitivity reaction disease injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLERGIC REACTION WOUND COMPLICATION

Contacts and locations

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Locations

Rush University Medical Center

Chicago, Illinois, 60612, United States

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