Rush University Medical Center
Clinical trials sponsored by Rush University Medical Center, explained in plain language.
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Could a single rinse replace antibiotics in penile implant surgery?
Disease control OngoingThis study compares two methods to prevent infections during first-time penile implant surgery for erectile dysfunction. One group receives the standard antibiotic rinse, the other uses Irrisept, a single antiseptic solution. Researchers will follow 200 men for one year after sur…
Phase: PHASE3 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated May 17, 2026 00:29 UTC
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Precision radiation targets prostate cancer with fewer side effects
Disease control OngoingThis study uses advanced MRI scans to guide radiation therapy for men with localized prostate cancer. Depending on whether a tumor is visible on the MRI, patients receive either a short course of radiation to the whole prostate or a longer treatment that boosts the dose to the tu…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated May 17, 2026 00:25 UTC
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New digital intervention aims to curb violence and substance use in black youth
Disease control OngoingThis study is testing a culturally tailored digital program called BrotherlyACT for young Black males aged 15-24 who have been hospitalized for injuries. The program aims to reduce aggression, substance use, and improve access to healthcare. Researchers will measure changes in be…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Could a simple bone marrow shot save your knee after surgery?
Disease control OngoingThis study tests whether injecting a concentrated sample of a patient's own bone marrow into the knee right after meniscus surgery can prevent or slow down arthritis. About 100 adults with a torn meniscus will receive either the bone marrow injection or a placebo (saline). Resear…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Apr 26, 2026 19:39 UTC
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Moms and daughters team up to fight obesity in black teens
Prevention OngoingThis study tests a program called Black Girls Move, designed to prevent obesity in Black teenage girls (9th and 10th grade) who are at risk. The program involves both daughters and their mothers, focusing on increasing physical activity and improving diet. Researchers will track …
Phase: NA • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated May 17, 2026 00:32 UTC
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Brain-Healthy diet may ward off dementia in stroke survivors
Prevention OngoingThis study tests whether a special diet called the MIND diet can help prevent memory loss and dementia in people who have had a stroke. Researchers will compare the MIND diet to usual post-stroke care in 250 adults aged 55 and older. The goal is to see if the diet protects the br…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated May 07, 2026 18:41 UTC
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Peer support trial aims to ease the burden of lewy body dementia caregivers
Symptom relief OngoingThis study tests whether trained peer mentors—people who have cared for a loved one with Lewy body dementia—can help current caregivers feel less stressed and more knowledgeable. About 500 caregivers will be randomly assigned to receive either weekly mentoring sessions or educati…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated May 17, 2026 00:26 UTC
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Gut health hope: probiotics tested as long COVID remedy
Symptom relief OngoingThis study tests whether taking probiotics can reduce symptoms and improve quality of life for people with Long COVID. About 180 adults with ongoing Long COVID symptoms will take probiotics or a placebo daily. The goal is to see if more people move from moderate-to-severe to mild…
Phase: PHASE2 • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated May 17, 2026 00:24 UTC
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Flu vaccine injected into tumors: breast cancer study pulled before starting
Knowledge-focused TerminatedThis early-stage study planned to test whether injecting a seasonal flu vaccine directly into breast cancer tumors is safe. It was designed for women with triple-negative or HER2+ breast cancer who were already scheduled for chemotherapy. However, the study was withdrawn before e…
Phase: PHASE1 • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 00:32 UTC
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New study tests if you can drive home after minor surgery
Knowledge-focused OngoingThis study looks at whether people can drive safely right after minor surgery with newer, short-acting anesthesia drugs. About 625 adults who have a valid driver's license and are having minor procedures will take a driving simulator test before leaving the clinic. The goal is to…
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 00:31 UTC
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Spine surgery aftermath: when does hip strength return?
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 22 adults who have spine surgery (LLIF or ALIF) for conditions like degenerative disc disease or herniated discs. Researchers measure hip and leg strength before surgery and at 6 weeks, 12 weeks, and 6 months after to find out exactly when weakness goes away. T…
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 00:25 UTC
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Hip implant showdown: does a new design raise metal levels?
Knowledge-focused OngoingThis study looks at whether a newer type of hip replacement implant (modular dual mobility) leads to higher levels of metals like cobalt, chromium, and titanium in the blood compared to a standard implant. About 52 adults getting a first-time hip replacement will be randomly assi…
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Gift cards or education: which gets patients to fill out surveys?
Knowledge-focused OngoingThis study looks at ways to improve how often patients complete follow-up surveys after shoulder surgery. About 400 adults having shoulder arthroscopy will either receive extra education about the importance of surveys or get Amazon gift cards for completing them. The goal is to …
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC