Rush University Medical Center
Clinical trials sponsored by Rush University Medical Center, explained in plain language.
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One-Week virtual therapy tested for PTSD relief
Disease control OngoingThis study is testing whether a one-week virtual therapy program is more effective than a one-week virtual relaxation program at reducing PTSD symptoms. Researchers are enrolling 140 adults with PTSD in Illinois to compare these two approaches. The goal is to understand how these…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Own blood used to patch lung leaks after cancer surgery
Disease control ENROLLING_BY_INVITATIONThis study tests whether using a patient's own blood as a patch can help seal air leaks that sometimes occur after lung cancer surgery. The trial involves 120 patients who still have an air leak three days after their operation. Researchers will compare outcomes between patients …
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Morning or night pill? UC study tests timing for better gut health
Disease control OngoingThis study is testing whether taking a common ulcerative colitis (UC) pill in the morning or evening works better to control hidden gut inflammation. It involves 32 adults with stable UC who will try taking their once-daily medication at one time for a month, then switch to the o…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New surgical wash challenges standard antibiotics in penile implants
Disease control OngoingThis study is testing if a single antiseptic wash called Irrisept works as well as a mix of traditional antibiotics at preventing infections during first-time penile implant surgery. It involves 200 men receiving a penile implant to treat erectile dysfunction. Researchers will co…
Phase: PHASE3 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Advanced MRI guides quicker, sharper radiation blast against prostate cancer
Disease control OngoingThis study is testing whether using advanced MRI scans to guide radiation therapy can improve treatment for prostate cancer. The goal is to deliver a stronger, more focused dose of radiation in a shorter time—either 5 or 28 sessions—depending on what the MRI scan shows. Researche…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New program aims to close the racial gap in diabetes care
Disease control OngoingThis study is testing a new support program to help African American and Latinx patients better manage their type 2 diabetes. It provides remote glucose monitoring, a support team, and tailored education to see if this approach improves blood sugar control more than standard care…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Can fun activities fight depression? new program brings hope to underserved communities
Disease control ENROLLING_BY_INVITATIONThis study is testing a new community outreach program designed to help people with depression in underserved neighborhoods. The program encourages participation in fun, rewarding social and recreational activities, aiming to improve mood, increase physical activity, and support …
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Stem cells aim to speed up knee surgery recovery
Disease control ENROLLING_BY_INVITATIONThis study is testing whether adding a patient's own stem cells during ACL reconstruction surgery helps the new ligament heal faster and stronger. It will enroll 100 adults with recent ACL tears who are scheduled for surgery. Researchers will use MRI scans and patient surveys to …
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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New hip implant design under scrutiny for potential metal leak
Disease control OngoingThis study is comparing two types of hip replacement parts to see if one causes higher levels of metal in the blood. It involves 52 adults with osteoarthritis who are getting a total hip replacement. Researchers are measuring cobalt, chromium, and titanium levels in the blood to …
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Flu shot fights cancer: doctors test direct tumor injection
Disease control TerminatedThis early-stage study aimed to test whether injecting seasonal flu vaccine directly into breast cancer tumors is safe. The approach was being tested in women with triple-negative or HER2-positive breast cancer who were scheduled for chemotherapy. Researchers planned to give incr…
Phase: PHASE1 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 13, 2026 15:06 UTC
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Moms and daughters team up to fight obesity in groundbreaking health program
Prevention OngoingThis study tests a 12-week program called 'Black Girls Move' designed to prevent obesity in Black teenage girls. The program involves both the girls and their mothers, focusing on setting goals for better physical activity and healthier eating. Researchers want to see if this fam…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated Mar 30, 2026 14:30 UTC
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Simple cup could slash infection risk for vulnerable women
Prevention OngoingThis study is testing whether providing menstrual cups to economically vulnerable women in Kenya can help prevent bacterial vaginosis and sexually transmitted infections (STIs). The researchers believe that using a clean, reusable cup for menstruation may replace unhygienic pract…
Phase: PHASE2 • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated Mar 17, 2026 12:55 UTC
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Can experienced caregivers ease the burden for others facing lewy body dementia?
Symptom relief OngoingThis study is testing a support program for family members caring for someone with Lewy body dementia (LBD). It aims to see if connecting current caregivers with trained, experienced 'peer mentors' and providing specific education can reduce caregiver stress and improve the quali…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Gut health solution for lingering COVID? probiotic trial seeks answers
Symptom relief OngoingThis study is testing whether probiotic supplements can help people with Long COVID feel better. Researchers will give 180 participants either probiotics or a placebo for 4 months, then switch treatments, to see if probiotics reduce symptoms and improve daily life. The goal is to…
Phase: PHASE2 • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Mar 27, 2026 12:37 UTC
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Late-Night eating and booze: a dangerous mix for your gut?
Knowledge-focused OngoingThis study aims to understand how modern lifestyle habits, specifically drinking alcohol and eating meals at irregular or late times, might increase a person's risk for colorectal cancer. Researchers are studying 12 adults who have had certain colon polyps, having them follow dif…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Can you drive home after surgery? new study tests anesthesia effects
Knowledge-focused OngoingThis study aims to find out if patients can drive safely immediately after minor outpatient surgery using short-acting sedatives. Researchers will test different combinations of anesthesia drugs on about 625 people. They will use a driving simulator to measure weaving, reaction t…
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Doctors map the road to recovery after back surgery
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how long it takes for hip and leg strength to return after two common types of lower back surgery (LLIF or ALIF). Researchers will measure muscle strength in 22 patients before surgery and at several points afterward using a special device. The goal …
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Researchers probe hidden cause of transplant weight gain
Knowledge-focused TerminatedThis study aims to understand why people often gain significant weight after receiving a pancreas transplant. Researchers will follow 50 transplant patients to see if high levels of digestive enzymes from the new pancreas are linked to this weight gain. The goal is to gather know…
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC