Nerve block or talk therapy may prevent chronic pain in PTSD patients
NCT ID NCT05700279
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether reducing PTSD symptoms can prevent acute pain from turning into chronic pain. Researchers will give 345 adults either a nerve block injection (stellate ganglion block) or trauma-focused talk therapy (cognitive processing therapy). The goal is to see if these treatments lower pain intensity and PTSD symptoms over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Stellate Ganglion Block (nerve block injection) and Cognitive Processing Therapy (talk therapy)
What this could lead to
If it works, this could point toward a way to prevent chronic pain by treating PTSD early, reducing long-term suffering.
What could go wrong
This is an early-stage study with 345 participants, so results may not apply to everyone. The nerve block carries risks like injection site pain or rare complications, and talk therapy may not work for all.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Rush University Medical Center
RECRUITINGChicago, Illinois, 60612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••