Can a tiny brain region predict Alzheimer's decades early?
NCT ID NCT04403165
First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 33 times
Summary
This study looked at 30 healthy older adults to see if changes in a small brain area called the locus coeruleus could be an early sign of Alzheimer's disease. Researchers used brain scans, sleep tests, and spinal fluid analysis to measure brain function, sleep quality, and attention. The goal was to find new ways to detect Alzheimer's risk long before memory problems start.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Icahn School of Medicine Mount Sinai
New York, New York, 10029, United States
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NYU Grossman School of Medicine
New York, New York, 10016, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.