New hope for rare lung cancer mutation? daratumumab shows promise in early trial

NCT ID NCT05807048

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called daratumumab in 8 people with a specific genetic mutation (STK11/LKB1) in advanced non-small cell lung cancer who had already tried other treatments. The goal was to see if the drug could shrink tumors. The study was small and designed to find early signals of effectiveness, with a target of at least 20% of patients responding.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NYU Langone Health

    New York, New York, 10016, United States