Can statins or other drugs fix cholesterol problems in autoimmune disease?
NCT ID NCT01180361
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study examined why people with rheumatoid arthritis (RA) and lupus have a higher risk of heart attacks. Researchers collected blood samples from 176 participants and tested how statins and adenosine A2A receptor agonists affected cholesterol balance in cells. The goal was to understand whether these drugs could reduce the harmful effects of RA and lupus plasma on cholesterol processing, potentially lowering heart disease risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- statins and adenosine A2A receptor agonists
- What this could lead to
- If successful, this could point toward new ways to lower heart attack risk in people with rheumatoid arthritis or lupus.
- What could go wrong
- This was a lab-based study, not a treatment trial, so results may not directly translate to patient benefits. The findings are early and exploratory.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
NYU Langone Hospital - Long Island
Mineola, New York, 11501, United States
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