Silk bandage vs. skin glue: which is gentler after ACL surgery?

NCT ID NCT07217613

Recruiting now Symptom relief Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special silk dressing (SYLKE®) causes fewer skin problems like rashes, blisters, or redness compared to standard skin glue (Dermabond®) after ACL knee surgery. About 100 people aged 14 to 60 having ACL reconstruction will be randomly assigned to one of the two dressings. The main goal is to see which dressing leads to fewer skin complications in the first few weeks after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: silk fibroin-based incision dressing (SYLKE®)
What this could lead to: If it works, this could offer a more comfortable, less irritating wound dressing option for people recovering from ACL surgery.
What could go wrong: This is a small, early-stage trial focused on skin reactions, not on how well the surgery itself heals. The silk dressing may not prove better than standard glue, and results may not apply to other types of surgery.

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Conditions

The condition(s) this trial relates to.

allergic contact dermatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION

Contacts and locations

Locations

NYU Langone Health
RECRUITING

New York, New York, 10016, United States

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