Jail study tests monthly shot to keep opioid treatment on track after release

NCT ID NCT06051890

Recruiting now Disease control Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study tests whether starting a monthly extended-release buprenorphine injection (Sublocade) in jail helps people with opioid use disorder stay on treatment after release. Two hundred men entering jail with a daily buprenorphine prescription will be randomly assigned to either switch to the monthly shot or stay on daily pills. Researchers will track how many leave jail with at least 7 days of buprenorphine in their system and how many continue treatment in the community.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Extended-release buprenorphine (Sublocade injection)
What this could lead to: If successful, this could show that starting a monthly buprenorphine shot in jail helps more people continue their opioid use disorder treatment after release, reducing relapse and overdose risk.
What could go wrong: This is a single-site study with 200 men, so results may not apply to all populations. The intervention requires starting in jail, which may not be feasible everywhere. Risks include injection site reactions and potential for diversion.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID-USE DISORDER

Contacts and locations

Locations

Baystate Health
RECRUITING

Springfield, Massachusetts, 01199, United States
Middlesex County House of Corrections
RECRUITING

New Brunswick, New Jersey, 08902, United States
NYU Langone Health - 180 Madison Ave
RECRUITING

New York, New York, 10016, United States
Tufts University Health Sciences
RECRUITING

Boston, Massachusetts, 02111, United States

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