Jail study tests monthly shot to keep opioid treatment on track after release
NCT ID NCT06051890
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether starting a monthly extended-release buprenorphine injection (Sublocade) in jail helps people with opioid use disorder stay on treatment after release. Two hundred men entering jail with a daily buprenorphine prescription will be randomly assigned to either switch to the monthly shot or stay on daily pills. Researchers will track how many leave jail with at least 7 days of buprenorphine in their system and how many continue treatment in the community.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Extended-release buprenorphine (Sublocade injection)
What this could lead to
If successful, this could show that starting a monthly buprenorphine shot in jail helps more people continue their opioid use disorder treatment after release, reducing relapse and overdose risk.
What could go wrong
This is a single-site study with 200 men, so results may not apply to all populations. The intervention requires starting in jail, which may not be feasible everywhere. Risks include injection site reactions and potential for diversion.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baystate Health
RECRUITINGSpringfield, Massachusetts, 01199, United States
Contact
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Middlesex County House of Corrections
RECRUITINGNew Brunswick, New Jersey, 08902, United States
Contact Phone: •••-•••-••••
Contact
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NYU Langone Health - 180 Madison Ave
RECRUITINGNew York, New York, 10016, United States
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Tufts University Health Sciences
RECRUITINGBoston, Massachusetts, 02111, United States
Contact