Magic mushroom compound could help Hard-to-Treat opioid addiction

NCT ID NCT06796062

First seen Jan 10, 2026 · Last updated May 15, 2026 · Updated 20 times

Summary

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) can help people with opioid addiction who still use illegal opioids even while taking methadone. About 240 participants will receive a high, medium, or low dose of psilocybin and be followed for 24 weeks to see if they reduce or stop opioid use. The goal is to improve treatment for those who haven't had success with standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OPIOID USE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke City Recovery Toolbox

    RECRUITING

    Albuquerque, New Mexico, 87102, United States

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • StartCare

    RECRUITING

    Brooklyn, New York, 11206, United States

  • University of New Mexico

    RECRUITING

    Albuquerque, New Mexico, 87106, United States

  • VIP Community Services, Inc

    RECRUITING

    The Bronx, New York, 10457, United States

Conditions

Explore the condition pages connected to this study.