Fruity vs. tobacco: which E-Cig flavor gets smokers to quit?

NCT ID NCT06264154

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the flavor of e-cigarettes helps smokers switch from regular cigarettes. 210 smokers who have tried to quit before will use fruit, tobacco, or menthol flavored e-cigarettes for 6 weeks. Researchers will track how many cigarettes they smoke and how satisfying the flavors feel.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

e-cigarettes with flavored nicotine pods (fruit, tobacco, or menthol)

What this could lead to

If successful, this could show which e-cigarette flavors make it easier for smokers to switch away from combustible cigarettes, potentially informing public health strategies.

What could go wrong

This is an early-stage observational study, not a treatment trial. Results may not apply to all smokers, and long-term health effects of e-cigarettes are still unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking nicotine dependence Smoking Tobacco Use Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••