THC may change how much you crave a cigarette, study finds

NCT ID NCT06609083

First seen Jan 16, 2026 · Last updated Jun 22, 2026 · Updated 28 times

Summary

This study looks at how THC, the active part of cannabis, affects cigarette cravings and smoking habits. Researchers will give 100 adults who smoke both tobacco and cannabis different doses of THC or a placebo, then measure how many cigarette puffs they take and how they feel. The goal is to learn more about the link between cannabis and tobacco use.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University Behavioral Pharmacology Research Unit

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

THC (tetrahydrocannabinol)

What this could lead to

If successful, this could help understand how cannabis use influences tobacco smoking, potentially guiding future treatments for dual use.

What could go wrong

This is an early-phase lab study with only 100 participants, so results may not apply to real-world settings or lead to immediate treatments.

Conditions

The condition(s) this trial relates to.

cannabis dependence Cigarette Smoking Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.