THC may change how much you crave a cigarette, study finds

NCT ID NCT06609083

Recruiting now Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how THC, the active part of cannabis, affects cigarette cravings and smoking habits. Researchers will give 100 adults who smoke both tobacco and cannabis different doses of THC or a placebo, then measure how many cigarette puffs they take and how they feel. The goal is to learn more about the link between cannabis and tobacco use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: THC (tetrahydrocannabinol)
What this could lead to: If successful, this could help understand how cannabis use influences tobacco smoking, potentially guiding future treatments for dual use.
What could go wrong: This is an early-phase lab study with only 100 participants, so results may not apply to real-world settings or lead to immediate treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Cigarette Smoking nicotine dependence Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS USE CIGARETTE SMOKING TOBACCO USE

Contacts and locations

Locations

Johns Hopkins University Behavioral Pharmacology Research Unit
RECRUITING

Baltimore, Maryland, 21224, United States

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