CANNABIS USE

This study is testing if a non-invasive brain stimulation technique can reduce cravings for cannabis in people with schizophrenia. Researchers believe the brains of people with schizophrenia may be wired differently, making them more vulnerable to cannabis use. They will use targ…

This study is testing whether brief phone counseling from pharmacists can help people with HIV who drink alcohol and take multiple medications reduce their risk of falls and thinking problems. The program involves medication reviews, personalized risk discussions, and home alcoho…

This study is testing whether a brief, supportive counseling session (called 'Chat') is better than standard educational information at helping teens reduce risky alcohol or cannabis use. It will enroll about 500 teens, aged 12 to 17, who screen as being at risk. Researchers will…

This study is testing a new mobile health program designed to help young adults who use cannabis frequently. Participants will be randomly assigned to either use a program with personalized feedback and text messages for five weeks, or to receive standard online information about…

This study is testing whether varenicline (Chantix), a medication approved for quitting smoking, can also help people reduce or stop using marijuana. Researchers want to see if the medication works better than a placebo pill when combined with counseling for 200 adults in South C…

This study is testing a brief, computerized treatment program designed to help teenagers aged 13-17 who are seeking help for cannabis and/or alcohol use. The program aims to reduce substance use by targeting automatic impulses to approach drugs and alcohol. Researchers will measu…

This study is testing whether a special group therapy program can help people who have long-term muscle and bone pain and are using medical cannabis. The therapy focuses on understanding and expressing emotions, which researchers think might reduce pain and improve mood and daily…

This study aims to see if brain scans can predict how well teens respond to a cannabis treatment program. Researchers will scan the brains of 80 teens (ages 14-17) who use cannabis, then have them join 10 weeks of virtual sessions where they report use and take drug tests. Teens …

This study aims to understand the immediate relationship between cannabis use, withdrawal, and mental health in teenagers. Researchers will follow 200 adolescents (ages 12-18) who use cannabis frequently and have depression symptoms. Using smartphone surveys throughout the day, t…

This study is collecting information on how adults with cancer use cannabis to manage symptoms like pain and nausea. Participants use a mobile app to track their cannabis use, symptoms, and other medications over time. The goal is to gather real-world data to help patients and do…

This Yale University study uses special brain scans to understand how cannabis use affects brain connections in adults aged 50 and older. Researchers will scan the brains of 24 participants to measure changes in brain cell connections. The study aims to gather knowledge about can…

This study aims to understand how THC, the main active ingredient in cannabis, affects a person's desire to smoke cigarettes and their actual smoking behavior. Researchers at Johns Hopkins will give 100 adult participants who regularly use both cannabis and cigarettes different d…

This study aims to understand how regular cannabis use affects sedation during wisdom tooth surgery. Researchers will compare two groups—cannabis users and non-users—measuring how much anesthesia medication they need and how their bodies respond during the procedure. The goal is …

This study aims to understand how young adults (ages 18-24) use cannabis in their daily lives. Researchers will follow 350 regular cannabis users for two years, tracking what products they use, how much, and how often through a mobile app. The goal is to identify different patter…

This study aims to understand how alcohol, cannabis, or using both together affect brain activity and physical coordination. Researchers will measure brain waves and balance in about 100 adults who regularly use these substances. The goal is to find patterns that might help disti…

This study aims to understand how using cannabis and then stopping it affects sleep, the body's natural daily rhythms, and sensitivity to light. Researchers will compare 180 young adults who regularly use cannabis with those who don't, monitoring them at home and during lab visit…

This study aims to understand if using cannabis with lower THC (the main psychoactive compound) can improve memory and thinking skills in young adults who use it frequently. Researchers will recruit 110 participants aged 21-25 in San Francisco, provide incentives for them to swit…

This study aims to understand what happens in the body when people use marijuana and tobacco together. Researchers will measure drug levels in the blood and physical effects like heart rate in 48 healthy adults who regularly use both substances. The goal is to gather foundational…

This study aims to see if at-home saliva tests can reliably measure cannabis use in remote clinical trials. Researchers will recruit 200 young adults who use cannabis weekly to compare saliva test results with urine tests and self-reported use. The goal is to find easier, remote-…