Teen cannabis use and depression: brain scans reveal hidden links
NCT ID NCT06941298
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how cannabis use changes brain function in teenagers who also have depression. About 280 teens will have brain scans (fMRI) and answer questionnaires at the start and again one year later, with a second year of follow-up. The goal is to understand the connection between cannabis, mood, and brain activity, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help us understand how cannabis use changes brain activity in teens with depression, pointing toward better prevention or treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test a new therapy, and results may not apply to all teens or lead to immediate clinical changes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Nathan Kline Institute
NOT_YET_RECRUITINGOrangeburg, New York, 10962, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Miami Clinical Research Building
RECRUITINGMiami, Florida, 33136, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact