Cannabis users may need different sedation for wisdom teeth surgery

NCT ID NCT07423195

Recruiting now Knowledge-focused Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares cannabis users and non-users during wisdom tooth removal under IV sedation. Researchers will measure how much sedative medication is needed and track vital signs like heart rate and blood pressure. The goal is to understand if cannabis use changes how people respond to sedation, which could help doctors personalize care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabis (recreational marijuana/THC)
What this could lead to: If successful, this study could help dentists and anesthesiologists adjust sedation doses for patients who use cannabis, improving safety and comfort during wisdom tooth removal.
What could go wrong: This is an observational study, not a treatment trial. It only looks at differences between users and non-users, so it won't prove cause and effect. Results may not apply to other surgeries or patient groups.

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS USE MARIJUANA USAGE SEDATION AND ANALGESIA WISDOM TOOTH

Contacts and locations

Locations

University of Michigan School of Dentistry/ Oral and Maxillofacial Surgery
RECRUITING

Ann Arbor, Michigan, 48109, United States

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