SEDATION AND ANALGESIA

This study is testing whether specially trained radiologists can safely use a deep sedation drug called ketamine for certain imaging-guided procedures, instead of requiring full general anesthesia with an anesthesiologist. Researchers want to see if this approach works well for p…

This study is testing two different approaches to sedation for people with severe COPD who need help breathing from a ventilator. Researchers want to see if using no sedation at all or briefly stopping sedation each day helps patients spend fewer days on the breathing machine. Th…

This study is testing if adding common non-opioid pain medications (like IV Tylenol and Toradol) can better control pain and reduce the need for strong opioid drugs in children who are critically ill and on a breathing machine. Researchers will enroll about 644 children aged 2 mo…

This study aims to find out if one of two commonly used pain and sedation medicines (fentanyl or hydromorphone) is better for adults in the ICU who need help breathing from a machine. Researchers will compare the drugs to see if one leads to patients needing less total medication…

This study aims to better understand how two common anesthesia drugs affect a patient's brain waves and stress response during a specific medical procedure called an ERCP. Researchers will monitor 20 patients using special sensors on the forehead and chest while they are under an…

This study aims to find out how common and how severe pain is for patients in intensive care who are on breathing machines (ventilators). Researchers will observe 370 patients to measure their pain levels and see if pain is linked to problems like longer time on the ventilator or…

This study aims to understand how regular cannabis use affects sedation during wisdom tooth surgery. Researchers will compare two groups—cannabis users and non-users—measuring how much anesthesia medication they need and how their bodies respond during the procedure. The goal is …