Could skipping sedation help COPD patients breathe on their own faster?

NCT ID NCT07146698

Recruiting now Disease control Sponsor: Benha University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at two ways to manage sedation in COPD patients who need a breathing machine (ventilator). One group gets no sedation at all, while the other has their sedation paused every day. The goal is to see which approach helps patients spend more days off the ventilator within the first 28 days. The study will include 60 adults with COPD who are on a ventilator in the ICU.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sedation interruption (behavioral intervention)
What this could lead to: If successful, this could show that reducing sedation helps COPD patients on ventilators breathe on their own sooner, shortening ICU stays.
What could go wrong: This is a small, early-stage study with only 60 participants, so results may not apply to all COPD patients. There is also a risk of discomfort or anxiety if sedation is reduced.

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Conditions

The condition(s) this trial relates to.

agnosia chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) SEDATION AND ANALGESIA

Contacts and locations

Locations

Benha University Hospitals
RECRUITING

Banhā, Qalyubia Governorate, 13518, Egypt

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