New sedative may cut ventilator time for ICU patients

NCT ID NCT05160987

Recruiting now Symptom relief Sponsor: Zhujiang Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two sedatives—remimazolam and midazolam—in 440 critically ill patients on breathing machines. The goal is to see if remimazolam helps patients come off the ventilator faster. Participants are randomly assigned to one drug, and researchers track how long they need mechanical ventilation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: remimazolam
What this could lead to: If it works, this could mean ICU patients on ventilators need less time on breathing machines, potentially reducing complications and speeding recovery.
What could go wrong: This is a mid-stage trial, so results may not confirm benefit. Sedation drugs can cause side effects like low blood pressure or breathing issues, and individual responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEDATION AND ANALGESIA

Contacts and locations

Locations

Department of Critical Care Medicine of Zhujiang Hospital,Southern Medical University
RECRUITING

Guangzhou, Guangdong, 510282, China

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