New sedative may cut ventilator time for ICU patients

NCT ID NCT05160987

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two sedatives—remimazolam and midazolam—in 440 critically ill patients on breathing machines. The goal is to see if remimazolam helps patients come off the ventilator faster. Participants are randomly assigned to one drug, and researchers track how long they need mechanical ventilation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

remimazolam

What this could lead to

If it works, this could mean ICU patients on ventilators need less time on breathing machines, potentially reducing complications and speeding recovery.

What could go wrong

This is a mid-stage trial, so results may not confirm benefit. Sedation drugs can cause side effects like low blood pressure or breathing issues, and individual responses vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Critical Care Medicine of Zhujiang Hospital,Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510282, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••