Which sedation is safer for Kids' heart procedures? new study aims to find out

NCT ID NCT07669012

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two drug combinations (ketamine with propofol vs. dexmedetomidine with propofol) for sedating children aged 2-12 during a heart catheterization to close simple heart defects. The goal is to see which approach causes fewer breathing problems and provides smoother recovery. 124 children will be enrolled to help doctors choose the best sedation method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketamine-Propofol and Dexmedetomidine-Propofol

What this could lead to

If successful, this could identify a safer sedation method for children undergoing heart procedures, reducing breathing complications.

What could go wrong

This is a small, early-phase study, so results may not apply to all children. Both sedation methods carry risks like breathing problems or low blood pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia atrial septal defect, ostium secundum type patent ductus arteriosus ventricular septal defect

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ain shams university hospital

    RECRUITING

    Cairo, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••