New study aims to spot heart defects in newborns with simple blood test

NCT ID NCT04667455

Completed Diagnosis Sponsor: Lund University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 313 children to see if blood tests and advanced heart scans could help detect congenital heart disease earlier and predict which children might need surgery. Researchers compared children with heart defects to healthy controls using blood biomarkers and non-invasive imaging. The goal is to improve early diagnosis and risk assessment for these young patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blood-based biomarker analysis and non-invasive cardiac imaging
What this could lead to: If successful, this could lead to earlier and more accurate detection of congenital heart disease in newborns and better prediction of which children will need surgery.
What could go wrong: This is an observational study, not a treatment trial. The findings may not change current care immediately, and the biomarkers may not be accurate enough for widespread use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortopulmonary window atrial septal defect cardiovascular disorder congenital heart disease congenital partial pulmonary venous return anomaly patent ductus arteriosus ventricular septal defect

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTOPULMONARY WINDOW ATRIAL SEPTAL DEFECT CARDIOVASCULAR DISEASES HEART DISEASE CONGENITAL PARTIAL ANOMALOUS PULMONARY VENOUS CONNECTION PATENT DUCTUS ARTERIOSUS VENTRICULAR SEPTAL DEFECT

Contacts and locations

Locations

Children's Heart Centre at Lund's University Hospital

Lund, Skåne County, 221 85, Sweden

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