SEDATION AND ANALGESIA
Clinical trials for SEDATION AND ANALGESIA explained in plain language.
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Which opioid is best for ventilated ICU patients? new trial aims to find out
Disease control CompletedThis study compares fentanyl and hydromorphone (Dilaudid) for sedating patients on mechanical ventilators in the ICU. About 300 adults will be randomly assigned to one of the two drugs. The main goal is to see if one leads to lower total opioid use. The results could help guide s…
Matched conditions: SEDATION AND ANALGESIA
Phase: PHASE2 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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New combo drug may cut painkiller use in ventilated newborns
Symptom relief CompletedThis study tested whether adding dexmedetomidine (a sedative) to fentanyl (a painkiller) could reduce the amount of fentanyl needed for full-term newborns on breathing machines. Forty babies were given either a lower fentanyl dose plus dexmedetomidine or standard fentanyl alone. …
Matched conditions: SEDATION AND ANALGESIA
Phase: PHASE2, PHASE3 • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Computer-Controlled sedation may protect elderly brains after surgery
Knowledge-focused CompletedThis study looked at 50 older adults (65+) having major surgery to see if using a computer-controlled sedation method (target-controlled infusion, or TCI) helps protect thinking and memory after the operation. Participants were split into two groups: one received TCI and the othe…
Matched conditions: SEDATION AND ANALGESIA
Sponsor: Namigar Turgut • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC