Computer-Controlled sedation may protect elderly brains after surgery
NCT ID NCT07311447
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 50 older adults (65+) having major surgery to see if using a computer-controlled sedation method (target-controlled infusion, or TCI) helps protect thinking and memory after the operation. Participants were split into two groups: one received TCI and the other received manual sedation. Their cognitive function was tested before and after surgery. The goal is to find safer ways to sedate elderly patients and reduce the risk of confusion or memory problems after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
target-controlled infusion (TCI) of sedatives and analgesics
What this could lead to
If successful, this could point toward safer sedation methods that reduce cognitive decline after surgery in older adults.
What could go wrong
This is a small, completed observational study with only 50 participants, so results may not apply broadly. It does not test a new drug or treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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İstanbul Prof. Dr. Cemil Taşcıoğlu City Hospital
Istanbul, Turkey (Türkiye)