Spinal surgery anesthesia showdown: which method spares the brain?
NCT ID NCT07701187
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study compares two ways of giving intravenous anesthesia during spinal surgery — manual controlled infusion (MCI) and target controlled infusion (TCI) — to see which one better protects thinking and memory afterward. Researchers will test patients' cognitive function using standard assessments before and after surgery. The goal is to find out whether the method of delivering anesthesia affects the risk of postoperative cognitive problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- manual controlled infusion (MCI) and target controlled infusion (TCI) of propofol and remifentanil
- What this could lead to
- If one technique is found to reduce cognitive decline after surgery, it could help guide anesthesia choices to protect brain function.
- What could go wrong
- This is a small, early-stage study focused on measuring differences, not proving a treatment. Results may show no clear advantage for either method.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Bursa yüksek ihtisas eğitim ve araştırma hastanesi BURSA, Bursa, Türkiye, BURSA, Bursa 16310, BURSA, Bursa
Bursa, Bursa, 16310, Turkey (Türkiye)
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