Spinal surgery anesthesia showdown: which method spares the brain?

NCT ID NCT07701187

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study compares two ways of giving intravenous anesthesia during spinal surgery — manual controlled infusion (MCI) and target controlled infusion (TCI) — to see which one better protects thinking and memory afterward. Researchers will test patients' cognitive function using standard assessments before and after surgery. The goal is to find out whether the method of delivering anesthesia affects the risk of postoperative cognitive problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
manual controlled infusion (MCI) and target controlled infusion (TCI) of propofol and remifentanil
What this could lead to
If one technique is found to reduce cognitive decline after surgery, it could help guide anesthesia choices to protect brain function.
What could go wrong
This is a small, early-stage study focused on measuring differences, not proving a treatment. Results may show no clear advantage for either method.

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Conditions

The condition(s) this trial relates to.

Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bursa yüksek ihtisas eğitim ve araştırma hastanesi BURSA, Bursa, Türkiye, BURSA, Bursa 16310, BURSA, Bursa

    Bursa, Bursa, 16310, Turkey (Türkiye)

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