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Can a simple guide help clinicians better address youth substance use?

NCT ID NCT07725289

Not yet recruiting Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This study develops and pilot tests a written 'practice companion' designed to help clinicians and other trusted adults provide developmentally appropriate substance use care to youth ages 14 to 24. The companion offers practical guidance on cannabis, opioids, and other substances, with a focus on overdose prevention and harm reduction. Researchers will interview youth, families, and clinicians to assess whether the care is acceptable, useful, and feasible in hospital and community settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a written practice companion guiding clinicians in youth substance use care
What this could lead to
If successful, this practice companion could offer a practical tool to improve substance use care for adolescents and young adults, potentially reducing overdose risk.
What could go wrong
This is a small pilot study with only 60 participants, so results may not generalize. The intervention is behavioral and depends on clinician uptake, which may vary.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Drug Overdose Harm Reduction opiate dependence poisoning substance abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADOLESCENT SUBSTANCE USE CANNABIS USE CO-OCCURRING MENTAL HEALTH CONDITIONS DRUG OVERDOSE OPIOID USE DISORDER OVERDOSE PREVENTION SUBSTANCE USE SUBSTANCE-RELATED DISORDERS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Adolescent and Young Adult Medicine, Mass General Brigham for Children

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-••••

  • BC Children's Hospital

    Vancouver, British Columbia, V6H 3N1, Canada

    Contact Phone: •••-•••-••••

  • CHU Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

    Contact Phone: •••-•••-••••

  • Centre de Recherche du CHUM (CRCHUM)

    Montreal, Quebec, H2X 0A9, Canada

    Contact Phone: •••-•••-••••

  • Foundry (Foundry Central Office)

    Vancouver, British Columbia, Canada

    Contact Email: •••••@•••••

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