SUBSTANCE-RELATED DISORDERS
Clinical trials for SUBSTANCE-RELATED DISORDERS explained in plain language.
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New app aims to catch addiction relapse early
Disease control Recruiting nowThis study tests whether a digital tool can help people with substance use disorders stay on track during recovery. About 150 participants will either receive standard care or standard care plus the app, which monitors for early signs of relapse. The goal is to see if the app imp…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Clínica Nuestra Señora de la Paz • Aim: Disease control
Last updated May 17, 2026 11:35 UTC
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New program tackles drug use in rural parents by fixing social problems first
Disease control Recruiting nowThis study tests a program called Just Care for Families, designed to help parents in rural Oregon who are involved with child welfare services and struggle with opioid or methamphetamine use. The program combines drug treatment, mental health support, parenting training, and hel…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Peer power: new study tests buddy system to beat opioid addiction in rural america
Disease control Recruiting nowThis study tests a program called Peer Activate, where trained peer recovery specialists help people in underserved rural areas stick with their medication for opioid use disorder and cut down on using other drugs. The program uses a technique called behavioral activation to enco…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Maryland, College Park • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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VA tests new support program to help veterans beat addiction
Disease control Recruiting nowThis study looks at whether a six-session recovery program plus a home telehealth service can help veterans with alcohol or drug problems drink less and stay in treatment. About 195 veterans in a VA psychiatric unit will be assigned to one of three groups: the recovery program, t…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Can a Parkinson's patch curb cocaine cravings? new trial aims to find out
Disease control Recruiting nowThis study tests whether a skin patch containing rotigotine, a drug already approved for Parkinson's disease, can help people with cocaine use disorder cut down on cocaine use and improve thinking skills. About 40 adults aged 25-70 with moderate to severe cocaine use disorder wil…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated May 06, 2026 16:02 UTC
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New study aims to expand lifeline for families battling addiction
Disease control Recruiting nowThis study looks at how to bring a program called Just Care for Families to more counties in Oregon. The program helps parents who use opioids or methamphetamine reduce their substance use and work toward being reunited with their children. Researchers will test two strategies: a…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Disease control
Last updated May 04, 2026 16:18 UTC
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Can a family advocate help prevent addiction and trauma? new study aims to find out
Prevention Recruiting nowThis study is testing whether adding a family advocate to a proven parenting program can help prevent substance use and reduce childhood trauma in 36 communities. About 360 families with at least one adult caregiver and one adolescent will take part. The goal is to see if the ext…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: RTI International • Aim: Prevention
Last updated May 17, 2026 11:38 UTC
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Mindfulness may ease chronic pain and cut opioid dangers
Symptom relief Recruiting nowThis study tests two approaches for adults with chronic pain who take long-term opioids: a mindfulness program called MORE and patient-centered pain management visits. The goal is to see if these methods can reduce pain, improve quality of life, and lower the risk of opioid misus…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: PHASE3 • Sponsor: University of Utah • Aim: Symptom relief
Last updated May 17, 2026 11:37 UTC
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New VA program aims to boost social and physical health in struggling veterans
Symptom relief Recruiting nowThis study tests a 3-session program called Omnis Salutis for recent veterans with PTSD, depression, anxiety, or substance use. The program teaches veterans about whole health and how to communicate their needs to doctors and loved ones. Researchers want to see if it improves soc…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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10,000 volunteers needed for landmark smartphone study on addiction relapse
Knowledge-focused Recruiting nowThis study aims to build a large data repository by collecting information from 10,000 adults who have used alcohol or drugs in the past 30 days. Participants will use a smartphone app that tracks things like screen time, app usage, and movement, and complete daily and monthly su…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated May 17, 2026 11:37 UTC
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Rural montana study tests whether doulas can ease postpartum depression
Knowledge-focused Recruiting nowThis study looks at whether specially trained doulas can help pregnant people in rural Montana feel more confident and supported, and reduce symptoms of depression and anxiety after childbirth. About 75 participants will be split into three groups: one gets regular doula care, on…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Montana • Aim: Knowledge-focused
Last updated May 17, 2026 11:33 UTC
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New study tests simple chat to boost addiction treatment success
Knowledge-focused Recruiting nowThis study looks at whether a special counseling style called Motivational Interviewing, used during the first visit, helps adults with substance use problems show up for and complete their treatment program. About 150 people seeking outpatient addiction treatment will take part.…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of New Mexico • Aim: Knowledge-focused
Last updated May 17, 2026 11:32 UTC
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Data to the rescue: new study aims to curb overdoses by informing Decision-Makers
Knowledge-focused Recruiting nowThis study aims to help Oregon decision-makers—like health officials, community leaders, and policymakers—use up-to-date, easy-to-understand data to improve substance use services and prevent overdoses. Researchers will test a new strategy that provides these leaders with the dat…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Tribal communities test new mental health crisis training
Knowledge-focused Recruiting nowThis study tests a training program called First Face for Mental Health in seven Tribal Nations. About 1,000 community members aged 14 and older will take part. Half get the training right away, the other half wait six months. Researchers will compare surveys to see if the traini…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Cambridge Health Alliance • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Do drinks and drugs delay Life-Saving surgery? new study investigates
Knowledge-focused Recruiting nowThis study looks at whether alcohol, drugs, or pain medicine given before hospital arrival changes how doctors decide on surgery for people with penetrating belly injuries. Researchers will follow 363 patients at two trauma centers in Colombia, comparing those who had these subst…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Sponsor: Fundacion Clinica Valle del Lili • Aim: Knowledge-focused
Last updated May 12, 2026 13:40 UTC