SUBSTANCE-RELATED DISORDERS
Clinical trials for SUBSTANCE-RELATED DISORDERS explained in plain language.
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Jobs for sobriety: VA tests work programs to beat addiction
Disease control OngoingThis study tests whether referring Veterans in early recovery from substance use disorder to work-focused programs (like supported employment) helps them stay sober and function better. About 100 Veterans will be randomly assigned to get the work referral or usual treatment alone…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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New app aims to help women battling opioid addiction and abuse
Disease control ENROLLING_BY_INVITATIONThis early study tests a mobile health program called WINGS+++ for women who use opioids and have experienced intimate partner violence. The program includes three sessions on a tablet or smartphone with videos, exercises, and a peer navigator to help connect to services. Researc…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Dawn A. Goddard-Eckrich • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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New program aims to curb drug use in rural parents by tackling social needs
Disease control OngoingThis study tests a program called Just Care for Families, designed to help parents in rural Oregon who are involved with child welfare services and struggle with opioid or methamphetamine use. The program combines substance use treatment, mental health support, parenting training…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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VA tests new combo therapy to help veterans beat addiction
Disease control OngoingThis study looks at whether adding a six-session group recovery program and a 90-day home telehealth program can help veterans with substance use disorders drink less and use fewer drugs. About 195 veterans from a VA psychiatric unit will be randomly assigned to one of three grou…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Can a handbook ease the stress of loving someone with addiction?
Symptom relief OngoingThis study tests whether a self-help handbook called the 5-Step Method can help family members cope with the stress of a relative's drug or alcohol misuse. 24 adults in the US will be split into two groups: one gets the handbook, the other does not. The goal is to see if the prog…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Villanova University • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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New program aims to boost Veterans' social and physical health
Symptom relief OngoingThis study tests a program called Omnis Salutis for recent veterans with PTSD, depression, anxiety, or substance use disorders. The program teaches veterans to identify their health goals and communicate them to doctors and family. Researchers want to see if it improves social an…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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MRI scans reveal hidden effects of opioids on unborn babies
Knowledge-focused ENROLLING_BY_INVITATIONThis observational study follows pregnant women with opioid use disorder who are taking buprenorphine or methadone. Researchers use MRI scans of the placenta and fetal brain during the second and third trimesters, along with blood samples and developmental assessments after birth…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Sponsor: Senthil Sadhasivam • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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AI alert aims to curb opioid overdoses in real time
Knowledge-focused OngoingThis study tests a machine-learning tool that gives doctors a pop-up alert when they prescribe opioids to a patient at high risk of overdose. The alert explains why the patient is at risk and suggests safer options, like prescribing naloxone or referring to pain therapy. Research…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Data dashboards could help overdose review teams prevent deaths
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to improve how overdose fatality review teams work by giving them a data dashboard and training. Instead of reviewing just one or two cases at a time, teams will use near real-time data to spot patterns and make better recommendations. About 400 team members and l…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC