Cure My Disease

Don't miss your cure!

 Log in / Sign up

MRI scans reveal hidden effects of opioids on unborn babies

NCT ID NCT06415994

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Senthil Sadhasivam Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This observational study follows pregnant women with opioid use disorder who are taking buprenorphine or methadone. Researchers use MRI scans of the placenta and fetal brain during the second and third trimesters, along with blood samples and developmental assessments after birth, to understand how prenatal opioid exposure affects the baby. The goal is to identify biomarkers that could lead to safer treatments and better outcomes for both mother and child.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could point toward ways to reduce neonatal opioid withdrawal syndrome and improve long-term outcomes for children exposed to opioids before birth.
What could go wrong
This is an observational study, not a treatment trial, so it cannot directly change outcomes. Results may not apply to all populations or opioid treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BUPRENORPHINE DEPENDENCE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Narcotic-Related Disorders opiate dependence pregnancy disorder substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BUPRENORPHINE DEPENDENCE METHADONE DEPENDENCE NARCOTIC-RELATED DISORDERS OPIOID USE DISORDER PREGNANCY RELATED SUBSTANCE-RELATED DISORDERS

Contacts and locations

Locations

  • Riley Hospital for Children

    Indianapolis, Indiana, 46202, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.