PREGNANCY RELATED

This study looks at whether giving regular blood transfusions to pregnant women with sickle cell disease can reduce serious health problems for both mother and baby. About 50 women will be randomly assigned to receive either repeated transfusions or standard care during pregnancy…

This study looks at whether delivering medically tailored groceries to pregnant women on Medicaid can reduce food insecurity and lead to healthier babies. About 360 participants will receive home-delivered groceries, with some also getting extra nutrition education. Researchers w…

This study tests whether giving iron through a vein (IV) early in the second trimester works better than iron pills for treating anemia in pregnancy. About 80 pregnant women with mild iron deficiency will be randomly assigned to one of two treatments. The goal is to see which app…

This study tests a mobile app called BumptUp designed to help pregnant and postpartum women in rural Kentucky increase their physical activity. About 176 women will either use the app or receive an educational brochure. Researchers will track activity levels, weight, diet, blood …

This study tests whether a buprenorphine patch can reduce withdrawal symptoms in pregnant women with opioid use disorder when starting treatment. About 40 participants will receive either the patch or standard care during the required withdrawal period before taking buprenorphine…

This study compares two programs designed to reduce heart disease risks in Black women after pregnancy. Researchers will track changes in blood pressure and body weight at 6 weeks and 12 months after delivery. The goal is to find the best way to support heart health and reduce he…

This study looks at 900 women who want permanent birth control during a C-section. It compares two methods of removing the fallopian tubes: using a special energy tool versus traditional stitches. The goal is to see which method is safer and costs less.

This study is developing a blood test that can determine the father of a fetus without any risk to the pregnancy. It uses a small amount of fetal DNA found naturally in the mother's blood. The test is designed for situations where paternity is in question, such as after a sexual …

This study looks at how to better detect eating disorders in pregnant women. Current screening tools may confuse normal pregnancy-related eating concerns with actual eating disorders. Researchers will compare answers from 50 pregnant women with and without eating disorders to fin…

This study is testing a program called TENDAI4PrEP to help pregnant women in Zimbabwe take PrEP, a daily pill that prevents HIV. The program combines problem-solving support to address barriers like depression and anxiety. About 132 pregnant women at risk for HIV will participate…

This study tests whether using a pelvic wand for perineal massage during late pregnancy and labor can help women feel more in control during childbirth and improve pelvic health. About 140 pregnant women planning to give birth at Beth Israel Deaconess Medical Center will particip…

This study compares two types of exercises—diaphragmatic breathing and pelvic stabilization—delivered via real-time telehealth to help postpartum women with pregnancy-related pelvic girdle pain. Sixty women who are at least 3 months postpartum and have pelvic pain will participat…

This study tests whether giving extra hormones (luteal phase support) after intrauterine insemination (IUI) with mild ovarian stimulation can increase the chance of a live birth. About 1008 couples with unexplained infertility will take part. The goal is to see if this simple add…

This study tests whether sexual counseling during pregnancy can improve sexual function, relationship adjustment, and emotional well-being. About 70 pregnant women will receive either standard care or two group counseling sessions. Researchers will measure changes in sexual healt…

This study will follow about 9,500 women of childbearing age in Kalifabougou, Mali, to track pregnancy outcomes and malaria infections. Researchers will collect data through regular health visits and surveys, but no new treatments or drugs are being tested. The goal is to better …

This study uses health insurance claims data to compare pregnancy outcomes in women with atopic dermatitis (eczema) who used ruxolitinib cream versus those who used a topical corticosteroid during pregnancy. Researchers will track over 5,600 women to see if there are differences …

This study looks at whether a program originally designed for clinics can work in community settings to help expecting mothers with healthy eating and exercise. Researchers will test the program with 60 pregnant women who have a BMI over 30. The goal is to see if the program is e…

This study is creating a registry of 1,000 pregnant women with autoimmune diseases like lupus and rheumatoid arthritis. Researchers will track their health and pregnancy outcomes to identify risk factors and ways to improve care for both mothers and babies. The study does not tes…

This study follows people of any age who have taken the drug odevixibat while pregnant or breastfeeding. Researchers will collect routine medical data to check for any effects on the mother, developing baby, or infant. No extra tests or visits are required beyond normal care. The…

This study aims to develop a smarter computer program that can separate a baby's heartbeat from the mother's heartbeat using signals from a belly sensor. Researchers will collect recordings from 350 pregnant women in their second or third trimester. The goal is to make fetal moni…

This study looks at how mothers with HIV in the United States decide to feed their babies, whether by breastfeeding or formula. Researchers will interview and survey about 1,150 mothers and their families to understand the medical, social, and personal factors behind these choice…

This study uses MRI scans to measure pancreas size in pregnant women and their babies. Researchers want to see how the pancreas changes during pregnancy and how diabetes might affect those changes. The study will follow 87 women from early pregnancy until one year after birth.

This study follows about 958 pregnant women with mild to moderate eczema to see if using ruxolitinib cream affects pregnancy or baby health. Researchers compare those who used the cream with those who did not, focusing on birth defects and other outcomes. The goal is to gather sa…

This study aims to map how genes are turned on and off in different cells of the placenta during early pregnancy and at childbirth. Researchers will collect small tissue samples from 100 pregnant women to analyze cell communication and development. The goal is to better understan…

This study follows 100 pregnant women with opioid use disorder who are already receiving standard treatment. Researchers will track whether mothers relapse or if their babies develop withdrawal symptoms (NOWS). The goal is to find better ways to predict and prevent these outcomes…

This study looks at how pregnant and non-pregnant patients recover after being in the intensive care unit (ICU) for COVID-19 and lung failure. Researchers will check for problems with movement, thinking, and mental health 3 to 6 months after the ICU stay. The goal is to better un…

This study tests whether a tool called MyPath helps women with substance use disorder make and stick with a birth control plan after giving birth. About 400 women will use the tool or receive standard care. The goal is to see if MyPath improves consistent use of effective contrac…

This study monitors the safety of the heart medication mavacamten when taken during pregnancy or while breastfeeding. Researchers will track outcomes for mothers, fetuses, and infants up to one year after birth. The goal is to better understand any risks, not to test a new treatm…

This study follows 825 pregnant women who need blood thinners for blood clots. Researchers will track how doctors manage these medications around childbirth and the weeks after. The goal is to find the safest approach to prevent bleeding while protecting mother and baby.

This study tests whether wrist-worn fitness trackers can safely and effectively monitor pregnant women with congenital heart disease at home. Researchers will track heart rhythms and other vital signs to catch early warning signs of complications. About 50 participants will wear …

This study follows pregnant women who take tildrakizumab for approved conditions and compares them to pregnant women with the same condition who do not take the drug. Researchers track pregnancy outcomes and infant health up to one year after birth. The goal is to understand if t…

This study looks at whether simulation training for doctors, nurses, and midwives can reduce the number of cervical exams women receive during labor and make exam results more consistent. Over 1,100 healthcare providers and patients will take part. The goal is to improve care by …

This study looks at how room light affects labor in pregnant women. Researchers think that darkness or red light may help labor progress, while bright light might slow it down. About 100 healthy pregnant women will use a home monitor to track contractions and report their lightin…

This study follows 60 women with neuromyelitis optica spectrum disorder (NMOSD) who received UPLIZNA during pregnancy or within six months before conceiving. Researchers will collect data on pregnancy outcomes, including birth defects, preterm birth, and infant development over 1…

This study looks at whether pregnant women with complications (like high blood pressure or slow fetal growth) can use a remote device to monitor their baby's heart rate from home. About 60 participants will use the device daily and report their symptoms via a phone app. The goal …

This study is working with community groups to adapt a program called Staying Healthy After Childbirth (STAC) so it better meets the needs of Black women and birthing persons. The goal is to improve blood pressure monitoring and overall health after pregnancy. Researchers will in…

This study tests whether small wearable sensors can safely track movement and walking in 30 pregnant women during early labor with a low-dose epidural. The goal is to see if these sensors can help monitor pain relief, predict falls, and understand labor progress. It is a first st…

This study is testing a new camera technique called Mueller polarimetric colposcopy to see if it can predict preterm birth. The camera looks at changes in the cervix during pregnancy. Researchers will study 683 pregnant women, both at low and high risk of preterm birth, to find p…

This study interviews 60 women who gave birth in French-speaking Belgium within the past year to understand why they chose their birthplace (home, birth center, or hospital) and how their birth experience was. Researchers also talk to birth companions like doulas and midwives to …

This study tracks 242 pregnant women to measure how the heart and blood vessels adapt during pregnancy and after childbirth. Researchers use non-invasive tests like heart rate monitoring and blood pressure checks to understand normal changes and spot early signs of complications.…