Pregnant women with eczema needed for safety study on common cream

NCT ID NCT06259669

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows about 958 pregnant women with mild to moderate eczema (atopic dermatitis) who use ruxolitinib cream (Opzelura) and compares them to similar women who do not use the cream. Researchers track birth defects and other pregnancy outcomes to see if the cream is linked to any problems. The goal is to gather real-world safety data, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ruxolitinib cream (Opzelura)

What this could lead to

If this study shows no increased risk of birth defects, it could provide reassurance about using ruxolitinib cream during pregnancy.

What could go wrong

This is an observational registry, not a controlled trial, so it cannot prove safety. Results may be influenced by other factors, and the study is still recruiting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema pregnancy disorder Pruritus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Syneos Health (remote site)

    RECRUITING

    Morrisville, North Carolina, 27560, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••