PREGNANCY RELATED

This study tests whether giving pregnant women a daily vitamin B12 supplement (50 micrograms) from early pregnancy until six months after birth helps their children grow and think better. Researchers are enrolling 800 pregnant women in Nepal who are at risk of low B12 levels. The…

This study tests a special care program for pregnant women with sickle cell disease in Ghana. A team of obstetric and sickle cell experts works together to prevent complications and reduce deaths. Researchers will track 500 women to see if this low-cost approach improves survival…

This study looks at whether a daily probiotic supplement can improve blood sugar control and limit weight gain in pregnant women who are overweight. About 84 women in early pregnancy will take the supplement or a placebo. The goal is to see if probiotics can help manage metabolic…

This study tests a program that connects pregnant women with opioid use disorder to a team of doctors, peer supporters, and community resources like doulas and home visiting. The goal is to improve treatment during pregnancy and reduce the need for medication in newborns experien…

This study tests whether providing 10 healthy, home-delivered meals per week plus brief weekly coaching can help pregnant women with overweight or obesity avoid gaining too much weight. Researchers will track weight changes and also measure food security and stress. The study is …

This study tests whether a weight loss program for overweight or obese women (and their partners) before pregnancy can reduce the risk of their child becoming overweight. 240 couples are randomly assigned to either a very low-calorie diet and counseling or no intervention. The ma…

This study tests whether helping women with overweight or obesity adopt a healthy lifestyle before and during pregnancy can reduce the risk of their children developing obesity. About 360 women planning pregnancy will either receive a tailored program including a low-calorie diet…

This study tests a mobile app called Next4You designed for teens aged 16-19 in California's foster care system. The app offers short lessons on communication, relationships, sexual health, and wellness over four weeks. Researchers want to see if it helps teens avoid unintended pr…

This study tests whether a prenatal yoga app called Down Dog can help pregnant African American women feel better mentally and physically. Over 12 weeks, 50 first-time mothers will use the app at home, wear a fitness tracker, and complete surveys. The goal is to see if the app is…

This study tests a program called Well-Mama, where community doulas use a checklist to help pregnant women get better care. About 576 pregnant women who are uninsured or on Medicaid will either receive standard care or standard care plus the Well-Mama support. The goal is to see …

This study tests a group prenatal care program called EleVATE GC for African-American women at high risk for postpartum depression. The program aims to reduce depression, preterm birth, and low birthweight by providing support and addressing stress. Researchers will compare outco…

This study tests whether a simplified behavioral relaxation program can improve sleep in pregnant women with insomnia. Twenty women in their second or third trimester will receive coaching calls and sleep hygiene tips. The goal is to see if this approach helps them fall asleep fa…

This study aimed to develop better MRI scanning methods for imaging fetuses during pregnancy. The goal was to improve image quality and make scans faster and more accurate, even when the baby moves. However, the study was withdrawn before any participants were enrolled, so no res…

Many pregnant women have experienced trauma, which can make prenatal care stressful and increase health risks. This study will create and test a toolkit to train obstetric providers in trauma-informed care, including screening tools and modified procedures. Researchers will work …

This registry enrolls up to 1,000 women aged 12–55 with rheumatic or autoimmune diseases who are pregnant or planning pregnancy. Researchers will collect data from medical records and patient surveys to study pregnancy outcomes, disease activity, and medication use. No experiment…

This study looks at how well pregnant women in Tanzania like and tolerate different amounts of iron in their daily prenatal vitamins. 156 women will try three different iron doses (30 mg, 45 mg, and 60 mg) and report which one they prefer and any side effects. The goal is to find…

This study follows 180 pregnant women to see how changes in their body fat during pregnancy relate to their baby's body fat at birth. Researchers use MRI scans and weight tracking to understand early influences on childhood obesity. The goal is to learn more about how the womb en…

This study looks at how the bacteria in a pregnant woman's gut (her microbiome) and her nutrition affect her baby's growth and health. Researchers are following 800 young pregnant women (28 and under) in Toronto throughout pregnancy and for a year after birth. They collect stool,…

This pilot study tests whether providing food boxes and extra money for healthy groceries can reduce food insecurity and improve birth outcomes for pregnant people on Medicaid. About 124 participants will receive either food delivery or financial support, along with recipes and h…

This study looks at whether a woman's insurance status affects how well her epidural works during a C-section. Researchers will review the medical records of 2,500 pregnant women at the University of Alabama at Birmingham. The goal is to uncover any unfair differences in pain man…

This study tests whether a culturally tailored mobile health program can improve mental health and pregnancy outcomes in Black pregnant women. Half of the 150 participants will receive the program, which builds communication and self-advocacy skills and provides support. The goal…

This study looks at how eating fermented and fiber-rich foods during pregnancy changes the gut bacteria of mothers and their babies. Researchers will track 135 pregnant women and their infants to see if diet affects the types of bacteria passed from mom to baby. The goal is to le…

This study was designed to see if giving pregnant women nutrition advice based on their unique biology, lifestyle, and health could improve their health and their baby's health. It planned to enroll women less than 20 weeks pregnant, excluding those with high-risk conditions. How…

This study tests a program to help prenatal clinics improve how they measure and treat high blood pressure in pregnant and postpartum patients. About 4,000 clinic staff from North Carolina will receive training, coaching, and practice sessions. Researchers will check if the progr…

This study follows 285 pregnant women with cystic fibrosis to see how CFTR modulators affect lung function during and after pregnancy. Researchers will measure breathing capacity before, during, and up to two years after delivery. The goal is to better understand how these medica…

This registry follows 75 pregnant women with heart disease to better understand the risks and outcomes for both mother and baby. Researchers will track health data for one year and check vital status at five years. The goal is to fill knowledge gaps and improve future care for th…

This study examines head and neck cancers that occur during pregnancy or within 12 months after giving birth. Researchers will check for certain viruses (HPV and EBV) and look at tumor types and pregnancy complications. The goal is to better understand these rare cases, not to te…