New study tracks safety of heart drug mavacamten in pregnancy

NCT ID NCT05939700

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study is looking at the safety of the heart medication mavacamten when taken during pregnancy or while breastfeeding. Researchers will follow about 20 people who have taken at least one dose of mavacamten during pregnancy or breastfeeding, tracking outcomes for both the mother and baby up to one year after birth. The goal is to better understand any risks or complications, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Mavacamten

What this could lead to

If this study succeeds, it could provide important safety information about using mavacamten during pregnancy and breastfeeding, helping doctors and patients make informed decisions.

What could go wrong

This is a small observational study with only 20 participants, so results may not apply to everyone. It is designed to gather data, not to test a new treatment, so no direct health benefits are expected for participants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREASTFEEDING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Breast Feeding hypertrophic cardiomyopathy pregnancy disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • The Mavacamten Pregnancy Surveillance Program, PPD Inc

    RECRUITING

    Wilmington, North Carolina, 28401-3331, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••