Can therapy help pregnant women stay on HIV prevention? new study aims to find out.
NCT ID NCT05624931
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a short counseling program (about 4 sessions) designed to help pregnant and postpartum women in Cape Town, South Africa, keep taking their daily HIV-prevention pill (PrEP). Many women stop PrEP due to depression or trauma from violence. The program uses cognitive behavioral therapy (CBT) to improve coping and build healthy habits. Researchers will enroll 118 women to see if the program is feasible and acceptable, and whether it helps them stay on PrEP during pregnancy and after birth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Brief CBT-based behavioral intervention
What this could lead to
If it works, this could point toward a practical, low-cost way to help pregnant women at high HIV risk stay on PrEP by treating underlying depression and trauma.
What could go wrong
This is a small, early-stage pilot study (118 participants) testing feasibility and acceptability, not effectiveness. The intervention is still being developed, so results may not generalize or show clear benefit.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DEPRESSION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Boston University
NOT_YET_RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Gugulethu Midwife Obstetric Unit (MOU)
RECRUITINGCape Town, Western Cape, 8001, South Africa
Contact Phone: •••-•••-•••• Email: •••••@•••••