Pregnancy safety of narcolepsy drug pitolisant under scrutiny

NCT ID NCT05536011

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks pregnant women with narcolepsy who take pitolisant (Wakix) or other narcolepsy medications, as well as pregnant women without narcolepsy who take pitolisant. Researchers compare pregnancy outcomes, including birth defects, to see if the drug poses risks. The goal is to gather real-world safety data to guide treatment decisions during pregnancy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pitolisant (Wakix)

What this could lead to

If safe, this could provide reassurance for pregnant women needing narcolepsy treatment.

What could go wrong

This is an observational study, not a controlled trial, so it can show associations but not prove cause and effect. Results may take years.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

narcolepsy pregnancy disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Evidera (PPD)

    RECRUITING

    Morrisville, North Carolina, 28403, United States

    Contact