Patch could make opioid treatment start easier for pregnant women

NCT ID NCT05790252

Recruiting now Symptom relief Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a buprenorphine patch can reduce withdrawal symptoms when pregnant women with opioid use disorder start sublingual buprenorphine treatment. Forty participants will receive either a real patch or a sham bandage during the initial withdrawal period. Researchers will track withdrawal severity and treatment success through phone surveys and urine tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: buprenorphine transdermal patch
What this could lead to: If it works, this could offer a more comfortable way to start buprenorphine treatment for pregnant women with opioid use disorder, reducing withdrawal symptoms.
What could go wrong: This is a small early-phase trial with only 40 participants, so results may not apply to everyone. The patch might not reduce withdrawal better than current methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BUPRENORPHINE WITHDRAWAL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

opiate dependence pregnancy disorder substance withdrawal syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BUPRENORPHINE WITHDRAWAL OPIOID-USE DISORDER PREGNANCY COMPLICATIONS PREGNANCY RELATED PREGNANCY, HIGH RISK

Contacts and locations

Locations

Washington University in St. Louis
RECRUITING

St Louis, Missouri, 63124, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.