Patch could make opioid treatment start easier for pregnant women

NCT ID NCT05790252

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 33 times

Summary

This study tests whether a buprenorphine patch can reduce withdrawal symptoms when pregnant women with opioid use disorder start sublingual buprenorphine treatment. Forty participants will receive either a real patch or a sham bandage during the initial withdrawal period. Researchers will track withdrawal severity and treatment success through phone surveys and urine tests.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University in St. Louis

    RECRUITING

    St Louis, Missouri, 63124, United States

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

buprenorphine transdermal patch

What this could lead to

If it works, this could offer a more comfortable way to start buprenorphine treatment for pregnant women with opioid use disorder, reducing withdrawal symptoms.

What could go wrong

This is a small early-phase trial with only 40 participants, so results may not apply to everyone. The patch might not reduce withdrawal better than current methods.

Conditions

The condition(s) this trial relates to.

opiate dependence pregnancy disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.