Can blood transfusions protect pregnant women with sickle cell disease?

NCT ID NCT06979492

Recruiting now Disease control Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving regular blood transfusions during pregnancy can reduce sickle cell complications and pregnancy-related problems in women with sickle cell disease. About 50 pregnant women will be randomly assigned to receive transfusions or standard care. The goal is to see if transfusions lower hospital visits and improve outcomes for both mother and baby.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: red blood cell transfusion
What this could lead to: If it works, this could establish a standard practice to prevent serious complications in pregnant women with sickle cell disease.
What could go wrong: This is a small Phase 4 trial with only 50 participants, so results may not apply to all. Transfusions carry risks like allergic reactions or iron overload.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anemia pregnancy disorder sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PREGNANCY RELATED SICKLE CELL DISEASE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Grady Health System
RECRUITING

Atlanta, Georgia, 30303, United States

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