SUBSTANCE-RELATED DISORDERS
Clinical trials for SUBSTANCE-RELATED DISORDERS explained in plain language.
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Can mindfulness keep women in recovery? new study tests a tailored program
Disease control CompletedThis study tested a mindfulness-based program designed for low-income women in residential treatment for substance use disorders. The goal was to see if the program helps women stay in treatment and avoid returning to drug or alcohol use. Researchers enrolled 200 women and measur…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated May 17, 2026 08:55 UTC
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Peer power: new study tests buddy system for opioid recovery
Disease control CompletedThis study tested whether a trained peer recovery specialist could help low-income, minority individuals stay on their methadone treatment for opioid use disorder. The approach used a brief behavioral activation program called Peer Activate, compared to usual care. 200 participan…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Maryland, College Park • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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Personality-Targeted program shows promise in preventing teen drug use
Prevention CompletedThis study tested a school-based program called Preventure in 3,900 Canadian 7th graders. The program targets four personality traits linked to substance abuse risk, aiming to delay or prevent alcohol and drug use. Researchers also measured whether delaying substance use helps pr…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: St. Justine's Hospital • Aim: Prevention
Last updated May 17, 2026 08:46 UTC
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Can a 1-Hour online chat keep teens from driving drunk or high?
Prevention CompletedThis study tested a single-session web program called webCHAT to see if it could reduce impaired driving among teens. About 200 adolescents aged 15.5 to 17 who were enrolled in driver education took part. The program aimed to help them avoid driving under the influence of alcohol…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Stanford University • Aim: Prevention
Last updated May 14, 2026 12:06 UTC
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CBD shows promise in easing opioid cravings and anxiety
Symptom relief CompletedThis study looked at whether CBD (a cannabis compound) can lower craving and anxiety in people with opioid use disorder who are already on methadone. 66 adults received either CBD or a placebo, and brain scans were used to see how CBD affects brain activity. The goal was to under…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: PHASE2 • Sponsor: Yasmin Hurd • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Personalized craving scale shows promise in addiction treatment
Symptom relief CompletedThis study tested whether adding a personalized therapy scale to standard addiction treatment helps reduce cravings. 151 adults with substance use or behavioral addictions participated. The approach aimed to identify each person's unique triggers to tailor their care.
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Step up to sobriety: fitness trackers boost mood in alcohol recovery
Symptom relief CompletedThis study looked at whether using an activity tracker (like a Fitbit) can help people in a hospital program for alcohol use disorder become more active and improve their emotional well-being. 90 adults wore the tracker during their stay. Researchers measured how often they used …
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Oviedo • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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New workshop helps veterans reclaim life after service
Symptom relief CompletedThis study tested a workshop called STEP-Home for 221 post-9/11 Veterans who had trouble readjusting to civilian life. The workshop taught practical skills like managing emotions, solving problems, and paying attention, without calling it therapy to make it more welcoming. The go…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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AI tool aims to catch hidden substance abuse in hospitals
Knowledge-focused CompletedThis study developed a computer program that scans hospital records to find patients who may be misusing drugs or alcohol. Researchers tested it on nearly 65,000 adults admitted to the hospital. The goal was to see if the tool could help doctors offer counseling or treatment to t…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 17, 2026 08:50 UTC
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Can a simple questionnaire improve depression screening in addiction treatment?
Knowledge-focused CompletedThis study checked if a questionnaire called the Behavioral Activation for Depression Scale (BADS) works well for people with substance use disorders. Researchers looked at data from 289 adults in treatment to see if the scale is reliable and accurate. The goal was to better unde…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Sponsor: Lauro Gutiérrez Castro • Aim: Knowledge-focused
Last updated May 17, 2026 08:49 UTC
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AI uncovers hidden patterns in addiction: a step toward personalized treatment
Knowledge-focused CompletedThis study used artificial intelligence to analyze personality and behavior questionnaires from 155 adults in residential treatment for substance use disorder. The goal was to find hidden subgroups of patients that might need different treatment approaches. No treatment was given…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Sponsor: Lauro Gutiérrez Castro • Aim: Knowledge-focused
Last updated May 17, 2026 08:46 UTC
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Peer coaches tested to curb opioid use in Justice-Involved youth
Knowledge-focused CompletedThis pilot study looked at whether paraprofessional coaches (some with personal experience of substance use) can help young adults aged 18-26 who are involved in the justice system reduce their drug use. The study measured drug use through urine tests and self-reported confidence…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Can a digital program help families guide loved ones to opioid treatment?
Knowledge-focused CompletedThis study tested a digital version of a family training program called CRAFT, designed to help concerned family and friends encourage a loved one with opioid use disorder to seek treatment. 45 participants completed the program and reported whether their loved one entered treatm…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: We The Village, Inc. • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Could removing cigarette filter holes change smoking habits?
Knowledge-focused CompletedThis study looked at what might happen if cigarette filter ventilation holes were banned. Researchers had 142 smokers shop in a virtual store where prices changed to see how many cigarettes and other nicotine products they would buy. The goal was to help create better rules for t…
Matched conditions: SUBSTANCE-RELATED DISORDERS
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated May 06, 2026 16:02 UTC