New therapy aims to help teens battling addiction and anxiety

NCT ID NCT01117753

Completed Disease control Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new behavioral therapy called OPT-A for teenagers who have both substance use problems and mood or anxiety disorders. 140 teens aged 10-17 will receive either OPT-A or standard treatment. Researchers will track substance use and mental health for 18 months to see if the new therapy works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: OutPatient Treatment for Adolescents (OPT-A) - a behavioral therapy
What this could lead to: If successful, this could provide an effective treatment option for teens struggling with both substance use and mental health issues, improving their outcomes.
What could go wrong: This is a relatively small, early-stage trial (140 participants). The results may not apply to all teens, and the new therapy may not prove better than usual care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety disorder depressive disorder mood disorder substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DISORDER DEPRESSIVE DISORDER SUBSTANCE-RELATED DISORDERS

Contacts and locations

Locations

Medical University of South Carolina, Department of Psychiatry & Behavioral Sciences, Family Services Research Center

Charleston, South Carolina, 29425, United States

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