New therapy aims to curb Self-Harm in addiction

NCT ID NCT05476601

Completed Disease control Sponsor: Pakistan Institute of Living and Learning Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a culturally adapted therapy called CMAP Plus is practical and acceptable for people with substance use disorder who also self-harm. The therapy combines problem-solving skills with motivational interviewing and was delivered weekly for 12 weeks. The trial involved 80 participants across six cities in Pakistan and focused on recruitment and attendance rates, not on whether the therapy actually reduces self-harm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Culturally adapted problem-solving therapy plus motivational interviewing (CMAP Plus)
What this could lead to: If successful, this could provide a practical, low-cost therapy to help people with substance use disorder reduce self-harm behaviors.
What could go wrong: This is a small feasibility study (80 participants) testing whether the approach is acceptable and practical, not whether it works. Results may not apply outside Pakistan.

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Conditions

The condition(s) this trial relates to.

Self-Injurious Behavior substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SELF HARM SUBSTANCE-RELATED DISORDERS

Contacts and locations

Locations

Pakistan Recovery Oasis

Lahore, Pakistan

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