Monthly shot vs. daily pills: new hope for opioid treatment in rural america?

NCT ID NCT06023459

Completed Disease control Sponsor: Yih-Ing Hser Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a once-monthly injection (XR-BUP) works as well as daily pills (SL-BUP) for treating opioid use disorder in rural settings. 140 adults with moderate to severe opioid use disorder took part. The goal was to see if the injection is practical and acceptable in rural clinics, and how it compares in reducing opioid use.

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Conditions

The condition(s) this trial relates to.

Narcotic-Related Disorders opiate dependence substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

AppleGate Recovery El Dorado

El Dorado, Arkansas, 71730, United States
Gibson Area Hospital and Health Services - Gibson Recovery Optimizing Wellness

Gibson City, Illinois, 60936, United States
New Beginnings Recovery Clinic & Behavioral Health Center

New Martinsville, West Virginia, 26155, United States
Oregon Health & Science University Primary Care Clinic, Scappoose

Scappoose, Oregon, 97056, United States
Penobscot Community Health Care Inc. - Seaport Community Health Center

Belfast, Maine, 04915, United States
Providence Northeast Washington Medical Group

Colville, Washington, 99114, United States
Southern Humboldt Community Healthcare District - Jerold Phelps Community Hospital

Garberville, California, 95542, United States

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