AI alert aims to curb opioid overdoses in real time
NCT ID NCT06810076
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a machine-learning tool that gives doctors a pop-up alert when they prescribe opioids to a patient at high risk of overdose. The alert explains why the patient is at risk and suggests safer options, like prescribing naloxone or referring to pain therapy. Researchers will compare outcomes before and after the tool is used in 13 clinics, involving about 674 patients and their doctors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Machine-learning based clinical decision support tool (Overdose Prevention Alert)
- What this could lead to
- If successful, this tool could help doctors identify patients at risk of opioid overdose and take steps to prevent it, potentially reducing overdose rates.
- What could go wrong
- This is a small pilot study in a few clinics, so results may not apply broadly. The tool might not change doctor behavior or reduce overdoses as hoped.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Florida Health Internal Medicine and Family Medicine
Gainesville, Florida, 32608, United States
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