Parkinson's drug patch could curb cocaine cravings
NCT ID NCT05886582
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a rotigotine skin patch (Neupro), already approved for Parkinson's disease, can help people with cocaine use disorder cut back on cocaine use when combined with behavioral therapy. Forty adults aged 25 to 70 with moderate to severe cocaine use disorder will receive either the patch or a placebo for six weeks. Researchers will measure cocaine use via urine tests and self-reports, and also check for improvements in brain activity and thinking skills.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Rotigotine (Neupro) transdermal patch
What this could lead to
If it works, this could point toward a new medication to help people with cocaine use disorder reduce their cocaine use and improve cognitive control.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply widely. The drug is not yet proven for this condition and may cause side effects like skin reactions or nausea.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Virginia Commonwealth University
RECRUITINGRichmond, Virginia, 23284, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••