CANNABIS USE

This study tests whether a six-session family-based intervention can reduce cannabis use and delinquent behavior in youth who are in a juvenile diversion program. The program focuses on improving parenting practices and parent well-being, with youth attending some sessions. Resea…

This study will test whether cannabis can reduce the severity of opioid withdrawal and make opioid use safer. One hundred adults with opioid use disorder will live in a hospital for about six weeks. Researchers will give them cannabis and a small dose of opioids to see how their …

This pilot study tests whether repetitive transcranial magnetic stimulation (rTMS) can strengthen a brain circuit linked to staying away from cannabis. Fifty treatment-seeking youth aged 15–21 with cannabis use disorder will receive either real or sham rTMS. Researchers will chec…

Stanford University is testing a free online toolkit called Smart Talk to see if it can prevent cannabis use among middle and high school students. The study will enroll 10,800 students across participating schools. The curriculum includes lessons, quizzes, and activities to chan…

This study is developing and testing a brief online program for young adult couples (ages 18-29) who use both alcohol and cannabis. The program aims to reduce risky substance use and improve relationship skills. Sixty couples in Washington State will be randomly assigned to eithe…

This study looks at how different doses of THC (the active ingredient in cannabis) affect eye movements and attention. Researchers will test 40 adults—some who use cannabis often and some who use it rarely—to see if eye-tracking can reliably detect impairment. The goal is to deve…

This early-stage study will give 32 healthy adults who use cannabis vaporized THC, beta-myrcene, or a placebo to see how these substances affect their feelings of being high and sleepy. Researchers want to learn how beta-myrcene, a compound found in cannabis and other plants, cha…

This study develops and pilot tests a written 'practice companion' designed to help clinicians and other trusted adults provide developmentally appropriate substance use care to youth ages 14 to 24. The companion offers practical guidance on cannabis, opioids, and other substance…

This study compares the immediate effects of inhaling cannabis (either smoked or vaporized) versus tobacco cigarettes on lung health. Researchers will measure breath biomarkers—such as exhaled nitric oxide, volatile organic compounds, and other substances—to see how each substanc…

This study will test whether cannabis can reduce the desire to take opioids in people with opioid use disorder. Thirty participants will live in a hospital for six weeks and receive either cannabis or a placebo, along with opioids. Researchers will measure how many times particip…

This study looks at how a moderate dose of THC (the active part of cannabis) affects mood, stress, and thinking in people who use cannabis at least once a week. Ninety adults will take part in two sessions—one with active cannabis and one with a placebo—without knowing which they…

This study will follow 90 people hospitalized with methamphetamine-induced psychotic disorder, comparing those who have also used cannabis in their lifetime to those who have not. Researchers will assess psychiatric symptoms, insight, addiction severity, and sleep quality weekly …

This study tests whether a brief education session about cannabis risks can increase knowledge and motivation to reduce use among people with eating disorders. 80 patients will receive either cannabis education or sleep hygiene education during their first week of a 20-week eatin…

This early-phase study will give 144 healthy young adults (ages 18-21) a single dose of THC (7.5 mg) or a placebo in a capsule, then use brain scans and behavioral tasks to measure how THC affects mood, reward processing, and learning. The goal is to understand why some people re…

This study is developing and testing a program called Cannabis Conversation Skills for Families (CCSF) that teaches family members communication skills to encourage their young adult loved one with first episode psychosis to reduce cannabis use. The program includes education abo…