Breath tests reveal how cannabis and tobacco differently impact lungs

NCT ID NCT07694466

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study compares the immediate effects of inhaling cannabis (either smoked or vaporized) versus tobacco cigarettes on lung health. Researchers will measure breath biomarkers—such as exhaled nitric oxide, volatile organic compounds, and other substances—to see how each substance affects the lungs. The study involves 12 healthy adults who are current recreational cannabis users and also smoke tobacco. Findings may help identify unique breath markers for cannabis versus tobacco exposure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cannabis (THC) and Tobacco
What this could lead to
If successful, this could help identify specific breath biomarkers that distinguish the lung effects of cannabis from tobacco, informing future health guidelines.
What could go wrong
This is a very small early-phase study (12 participants) and only measures immediate effects, not long-term health outcomes. Results may not apply to heavier or more diverse users.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Kentucky

    Lexington, Kentucky, 40508, United States

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