BIOMARKERS

This study is testing whether a simple saliva sample can help diagnose oral squamous cell carcinoma (OSCC), a type of mouth cancer. Researchers will look for specific DNA changes (methylation) in the saliva of 30 patients with OSCC and compare them to 30 healthy controls. If the …

This study is looking for new biological markers in the fluid that builds up around the lungs (pleural effusion) in people with lung adenocarcinoma. Researchers will compare these markers between cancerous and non-cancerous fluid samples from 100 patients. The goal is to see if t…

This study is testing whether a blood test measuring a protein called p-Tau217 can diagnose Alzheimer's disease as accurately as the current method, which requires a spinal tap. Researchers will compare results from blood and spinal fluid samples from 40 adults with suspected Alz…

This study follows 180 adults with cerebral small vessel disease to see how their condition changes over time after a stroke. Researchers will use MRI scans and blood tests to track disease progression and look for links to thinking skills, daily function, and stroke recurrence. …

This observational study will enroll 10,000 adults who are already scheduled for a cardiac CT scan. Researchers will use artificial intelligence to analyze the scans, looking for subtle signs of dangerous plaque that might predict future heart attacks. Participants will also give…

This study aims to create a 'biological age' calculator specifically for the Russian population. Researchers will collect health, lifestyle, and lab data from 3,500 volunteers aged 18 and older. The goal is to better understand aging and potentially predict age-related disease ri…

This study looks at blood clots removed from stroke patients during a procedure called thrombectomy. Researchers will also take a small blood sample. They want to see if the clot's makeup and blood markers can tell us more about what caused the stroke, how well treatment worked, …

This observational study will follow 500 adults and children in the DRC who come to the clinic with a fever. Researchers want to see if using a simple blood test (CRP), a WHO antibiotic guidebook, or electronic decision tools can help doctors prescribe antibiotics more appropriat…

This pilot study compares immediate versus delayed dental implant placement after tooth extraction. Researchers will measure healing-related molecules in saliva and gum fluid over 30 days in 24 adults. The goal is to understand how timing affects early healing, which could guide …

This study is testing whether adding blood and urine biomarkers to a computer risk score can better predict which hospitalized patients will develop severe acute kidney injury (AKI). Researchers will enroll 800 adults at high risk (top 10% by the risk score) and track them for th…

This observational study will analyze fluid from jaw cysts in 25 people to measure specific proteins (MMP-8, MMP-9, RANKL, MIP-1alpha). The goal is to learn more about how these cysts develop. Participants undergo no extra procedures beyond standard care.