BIOMARKERS

This trial investigates whether a rapid test for antibiotic resistance genes (integrons) can help doctors choose narrower-spectrum antibiotics for hospitalized adults with urinary tract infections (UTIs). Participants must have had a recent infection with a resistant bacterium. T…

This study tests whether immersive virtual reality (VR) can lower stress, anxiety, and pain in adults undergoing their first central or midline catheter insertion. Participants use a VR headset showing calming nature scenes during the procedure. The goal is to see if this distrac…

This study will test whether high-intensity interval training (HIIT) on a stationary bike can improve walking, balance, and thinking in people with multiple sclerosis (MS). Forty adults with mild to moderate MS will be randomly assigned to either HIIT or moderate-intensity contin…

This study looks at saliva from people with osteoporosis to measure certain immune markers and an enzyme called MMP-8. Researchers also check participants' dental cavities. The goal is to better understand how osteoporosis might affect oral health. No treatments are given—only sa…

This study looks for early signs of brain injury in newborns who experienced oxygen deprivation at birth (perinatal asphyxia). Researchers will use EEG brain wave monitoring and eye-tracking tests, along with blood markers, to see if they can detect damage sooner than current met…

This study compares the immediate effects of inhaling cannabis (either smoked or vaporized) versus tobacco cigarettes on lung health. Researchers will measure breath biomarkers—such as exhaled nitric oxide, volatile organic compounds, and other substances—to see how each substanc…

This study will collect blood samples from 1,000 people with small colon growths to see if a liquid biopsy can accurately tell benign from malignant lesions and predict cancer spread to lymph nodes. Current methods often lead to unnecessary surgery. The goal is to create a bioban…

This observational study will analyze blood samples from 1,000 former U.S. service members who were exposed to open-air burn pits during deployment, comparing them to unexposed veterans. Researchers will look at genes, proteins, and immune cells to find biological markers linked …

This study looks at three different ways to clean infected root canals in 66 men aged 18-35. The goal is to see which method best reduces signs of inflammation and infection. Researchers will measure certain proteins in the fluid around the tooth root before and after treatment.

This study looks at certain proteins (aquaporins and IL-8) in the fluid and tissue of healthy teeth and teeth with a painful, inflamed nerve (irreversible pulpitis). Researchers will collect samples from 70 adults during routine root canal treatment to compare protein levels. The…